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TranscriptomicsTranscription profiling human whole blood from children with pre-type1diabetes
Type 1 diabetes (T1D) is an autoimmune disease caused by selective destruction of insulin producing pancreatic beta-cells in the islets of the Langerhans. The progression to clinical diabetes is characterized by the appearance of autoantibodies against islet cells (ICA) and beta-cell-specific antige...
ORGANISM(S): Homo sapiens 
2010-03-31 | E-TABM-666 | biostudies-arrayexpress
TranscriptomicsGenome-wide expression kinetics of children with Type 1 diabetes (T1D) -associated autoantibodies or progression towards clinical T1D, compared to healthy matched controls .
To unravel genes and molecular pathways involved in the pathogenesis of type 1 diabetes (T1D), we performed genome-wide gene expression profiling of prospective venous blood samples from children developing T1D-associated autoantibodies or progressing towards clinical diagnosis. 357 peripheral blood...
ORGANISM(S): Homo sapiens 
2014-02-20 | E-GEOD-43488 | biostudies-arrayexpress
TranscriptomicsGenome-wide expression kinetics of children with T1D-associated autoantibodies compared to healthy matched controls I
To unravel genes and molecular pathways involved in the pathogenesis of type 1 diabetes (T1D), we performed genome-wide gene expression profiling of prospective venous blood samples from children developing T1D-associated autoantibodies or progressing towards clinical diagnosis. 63 peripheral blood ...
ORGANISM(S): Homo sapiens 
2014-02-20 | E-GEOD-30208 | biostudies-arrayexpress
TranscriptomicsGene expression changes during Type 1 diabetes pathogenesis
This SuperSeries is composed of the SubSeries listed below. Due to privacy concerns, the SNP data is not available with unrestricted access. Refer to individual Series
ORGANISM(S): Homo sapiens 
2014-02-20 | E-GEOD-30211 | biostudies-arrayexpress
TranscriptomicsGenome-wide expression kinetics of children with T1D-associated autoantibodies compared to healthy matched controls II
To unravel genes and molecular pathways involved in the pathogenesis of type 1 diabetes (T1D), we performed genome-wide gene expression profiling of prospective venous blood samples from children developing T1D-associated autoantibodies or progressing towards clinical diagnosis. 58 peripheral blood ...
ORGANISM(S): Homo sapiens 
2014-02-20 | E-GEOD-30209 | biostudies-arrayexpress
TranscriptomicsGenome-wide espression kinetics of children progressing to clinical Type 1 diabetes (T1D).
To unravel genes and molecular pathways involved in the pathogenesis of type 1 diabetes (T1D), we performed genome-wide gene expression profiling of prospective venous blood samples from children developing T1D-associated autoantibodies or progressing towards clinical diagnosis. 247 peripheral blood...
ORGANISM(S): Homo sapiens 
2014-02-20 | E-GEOD-30210 | biostudies-arrayexpress
ProteomicsD12_iTRAQ
D12_1 and D12_2 are 8 plex iTRAQ analyses of depleted serum samples. The files are mgf files of collected SCX fractions that were analyzed with an Orbitrap Velos- Proxeon capillary LC combination. HCD fragmentation was used.
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2014-06-24 | MSV000078759 | MassIVE
ProteomicsD14_LF
RAW files Case19T and Control19T represent D14 and Control-14 and are marked by their visit number. These are label free analyses of depleted serum samples conducted with an Orbitrap Velos- Proxeon capillary LC combination. CID fragmentation was used.
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2014-06-24 | MSV000078760 | MassIVE
ProteomicsD5_iTRAQ
D5_1 and D5_2 are 8 plex iTRAQ analyses of depleted serum samples. The files are ProteinPilot group files of collected SCX fractions that were analyzed with an Orbitrap Velos- Proxeon capillary LC combination. HCD fragmentation was used.
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2014-06-24 | MSV000078756 | MassIVE
ProteomicsD11_iTRAQ
D11_2 and D11_3 are 8 plex iTRAQ analyses of depleted serum samples. The files are mgf files of collected SCX fractions that were analyzed with an Orbitrap Velos- Proxeon capillary LC combination. HCD fragmentation was used.
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2014-06-24 | MSV000078758 | MassIVE
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