Sort   by:  
 Page size 
ProteomicsPROTEOLYTIC ACTIVITIES OF EXTRACELLULAR VESICLES ATTENUATE A-SYNUCLEIN AGGREGATION AND MODULATE ITS TOXICITY
Extracellular vesicles (EVs) are nano-sized lipid vesicles released from cells into the extracellular milieu. We examined the yet unexplored role(s) of EVs in α-synuclein (α-syn) degradation and recipient-cell homeostasis, and whether EVs can affect the processing of extracellular α-syn species, the...
ORGANISM(S): Mus musculus (Mouse) 
2025-10-06 | PXD044320 | Pride
Proteomics A-synuclein Extracellular vesicles Proteases 
ProteomicsDifferential intracellular trafficking of exosomes in microglia and astrocytes
Exosomes have emerged as key players in cell-to-cell communication in both physiological and pathological processes in the Central Nervous System. Thus far, the intracellular pathways involved in uptake and trafficking of exosomes within different cell types of the brain are poorly understood. In ou...
ORGANISM(S): Mus musculus (Mouse) 
2023-07-20 | PXD038287 | Pride
Brain-derived exosomes  α-synuclein ko mouse brain hemispheres (cd57bl6) 
ModelsOuzounoglou2014 - Modeling of alpha-synuclein effects on neuronal homeostasis
Ouzounoglou2014 - Modeling of alpha-synuclein effects on neuronal homeostasis This model is described in the article: In silico modeling of the effects of alpha-synuclein oligomerization on dopaminergic neuronal homeostasis. Ouzounoglou E, Kalamatianos D, Emmanouilidou E, Xi...
2024-09-02 | BIOMD0000000559 | BioModels
Sort   by:  
 Page size