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TranscriptomicsPlatform Comparison for miRNA
The goal of this study was to investigate the generation and normalization of microRNA expression data based on microarray technologies to comparatively assess their quality. Two profiling platforms were compared: the single-channel Affymetrix GeneChip(r) and the Exiqon dual-channel miRCURY LNA(tm),...
ORGANISM(S): Mus musculus 
2012-04-01 | E-MTAB-876 | biostudies-arrayexpress
TranscriptomicsPlatform Comparison for miRNA
The goal of this study was to investigate the generation and normalization of microRNA expression data based on microarray technologies to comparatively assess their quality. Two profiling platforms were compared: the single-channel Affymetrix GeneChip(r) and the Exiqon dual-channel miRCURY LNA(tm),...
ORGANISM(S): Mus musculus 
2012-04-01 | E-MTAB-875 | biostudies-arrayexpress
MetabolomicsComprehensive systems biology analysis of a seven-month cigarette smoke inhalation study in C57BL/6 mice
Smoking of combustible cigarettes has a major impact on human health. Using a systems toxicology approach in a model of chronic obstructive pulmonary disease (C57BL/6 mice), we assessed the health consequences in mice of smoke derived from a prototype modified risk tobacco product (pMRTP) as compare...
2015-11-19 | MTBLS143 | MetaboLights
TranscriptomicsAorta transcriptome of ApoE-/- mice exposed to mainstream cigarette smoke for 30 days.
Aorta gene expression profiles of smoke- and sham-exposed female ApoE-/- mice were analyzed to elucidate the biological networks perturbed by exposure to 600mg TPM/m3 for 4h per day, 5 days a week, for a period of 30 days. Aortic arches were dissected 24h after the last exposure.
ORGANISM(S): Mus musculus 
2015-01-12 | E-MTAB-1696 | biostudies-arrayexpress
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