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UnknownSemi-mechanistic modelling platform to assess cardiac contractility and haemodynamics in preclinical cardiovascular safety profiling of new molecular entities.
Not available
S-EPMC7348097 | biostudies-literature
ModelsMaurya2005_GTPaseCycle_reducedOrder
This model is according to the paper Reduced-order modeling of biochemical networks: application to the GTPase-cycle signalling module by Maurya et al 2006.The figure 4c is reproduced by Copasi 4.0.19 (development) .It is three-dimensional logarithmic plots show the output of simulati...
2024-09-02 | BIOMD0000000085 | BioModels
TranscriptomicsDnmt3a haploinsufficiency transforms Flt3-ITD myeloproliferative disease into a rapid, spontaneous, and fully-penetrant acute myeloid leukemia (Bulk RNA-Seq)
Cytogenetically normal acute myeloid leukemia (CN-AML) represents nearly 50% of human acute myeloid leukemia (AML) cases with a 5-year overall survival of approximately 30%. In CN-AML with poorer prognosis, mutations in the de novo DNA methyltransferase (DNMT3A) and the FMS-like tyrosine kinase 3 (F...
ORGANISM(S): Mus musculus 
2016-03-27 | E-GEOD-77846 | biostudies-arrayexpress
UnknownMethylglyoxal-induced glycation stress promotes aortic stiffening: putative mechanistic roles of oxidative stress and cellular senescence.
Not available
S-EPMC12705182 | biostudies-literature
TranscriptomicsDnmt3a haploinsufficiency transforms Flt3-ITD myeloproliferative disease into a rapid, spontaneous, and fully-penetrant acute myeloid leukemia (Single Cell RNA-Seq)
Cytogenetically normal acute myeloid leukemia (CN-AML) represents nearly 50% of human acute myeloid leukemia (AML) cases with a 5-year overall survival of approximately 30%. In CN-AML with poorer prognosis, mutations in the de novo DNA methyltransferase (DNMT3A) and the FMS-like tyrosine kinase 3 (F...
ORGANISM(S): Mus musculus 
2016-03-27 | E-GEOD-77847 | biostudies-arrayexpress
UnknownIn SilicoModel-driven Assessment of the Effects of Brain-derived Neurotrophic Factor Deficiency on Glutamate and Gamma-Aminobutyric Acid: Implications for Understanding Schizophrenia Pathophysiology.
Not available
S-EPMC5426484 | biostudies-literature
UnknownSchizophrenia and Corollary Discharge: A Neuroscientific Overview and Translational Implications.
Not available
S-EPMC6478093 | biostudies-literature
UnknownCould angiotensin-II induced T-cell senescence exacerbate age-related vascular dysfunction?
Not available
S-EPMC9012694 | biostudies-literature
UnknownKlotho enhances diastolic function in aged hearts through Sirt1-mediated pathways.
Not available
S-EPMC11336011 | biostudies-literature
UnknownAging, aerobic exercise, and cardiovascular health: Barriers, alternative strategies and future directions.
Not available
S-EPMC10068966 | biostudies-literature
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