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TranscriptomicsTranscription profiling of human acute myeloid leukemia patient samples
Expression profiles of acute myeloid leukemia patient samples. Blasts and mononuclear cells were purified from bone marrow or peripheral blood aspirates of acute myeloid patients. Samples contained 80-100 percent blast cells. Total RNA was extracted by lyses with guanidium isothiocyanate followed by...
ORGANISM(S): Homo sapiens 
2008-06-12 | E-GEOD-1159 | biostudies-arrayexpress
TranscriptomicsGenetic mosaic analysis of the tumorigenic process distinguishes cell of origin from cell of mutation
Cancer results from molecular mutations occurring in specific cell types, thus determining the cell-of-origin is critical for effective cancer treatment. Inferring such information from terminal tumors can be misleading because malignant tumor cells tend to acquire aberrant properties. Animal models...
ORGANISM(S): Mus musculus 
2011-07-01 | E-GEOD-26676 | biostudies-arrayexpress
Genomicsena-DATASET-ErasmusMC-13-07-2021-14:23:08:540-67 - samples
Collection of mostly matching primary and recurrent glioblastoma RNA-seq sample pairs, also matching with an earlier DNA sequencing study
EGAD00001007860 | EGA
GenomicsG-SAM: Transcriptional Evolution of Glioblastomas Treated With Standard of Care
Collection of mostly matching primary and recurrent glioblastoma RNA-seq sample pairs, also matching with an earlier DNA sequencing study
EGAS00001005436 | EGA
GenomicsFRONTIER DNA methylation
Tumor biopsies profiled by DNA methylation array
EGAD00010002182 | EGA
GenomicsSpatial concordance of DNA methylation classification in diffuse glioma
Background: Intratumoral heterogeneity is a hallmark of diffuse gliomas. DNA methylation profiling is an emerging approach in the clinical classification of brain tumors. The goal of this study is to investigate the effects of intratumoral heterogeneity on classification confidence. Methods: We use...
EGAS00001005434 | EGA
GenomicsVarn Lab Data Access Committee
Data Access Committee EGAC00001002214
EGAC00001002214 | EGA
TranscriptomicsEts factors regulate neural stem cell depletion and gliogenesis in Ras pathway-driven glioma
As the list of putative driver mutations in glioma grows, we are just beginning toAs the list of putative driver mutations in glioma grows, we are just beginning to elucidate the effects of dysregulated developmental signaling pathways on the transformation of neural cells. We have employed a postn...
ORGANISM(S): Mus musculus 
2015-05-28 | E-GEOD-69254 | biostudies-arrayexpress
GenomicsWhole Genomic Sequencing of Nine Primary Colorectal Adenocarcinoma Tumor/Germline Pairs

This study was the first-known effort to complete the complete genome sequencing of primary colorectal adenocarcinomas and the matched germline genome. Nine colorectal adenocarcinomas selected on the basis of having chromosomal instability were subjected to 'shotgun' Illumina sequencing w...

phs000374.v1.p1 | EGA
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