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TranscriptomicsAging Experiment
Lifelong murine gene expression profiles in relation to chronological and biological aging in multiple organs Five tissues: Kidney, Liver, Lung, Spleen, Brain. Six timepoints: 13wks, 26 wks, 52wks, 78wks, 104wks, 130wks. One Genotype: C57Bl/6, 3 replicates
ORGANISM(S): Mus musculus 
2013-07-10 | E-GEOD-34378 | biostudies-arrayexpress
UnknownSomaMutDB 2.0: A comprehensive database for exploring somatic mutations and their functional impact in normal human tissues.
Not available
S-EPMC12807692 | biostudies-literature
UnknownSingle-cell analysis reveals different age-related somatic mutation profiles between stem and differentiated cells in human liver.
Not available
S-EPMC6994209 | biostudies-literature
UnknownINK4 locus of the tumor-resistant rodent, the naked mole rat, expresses a functional p15/p16 hybrid isoform.
Not available
S-EPMC4313802 | biostudies-literature
TranscriptomicsTranscription profiling of liver from Ercc1-/- mice and wild type littermates to investigate features of premature aging
To investigate the cause of the premature aging features in the Ercc1-/- mouse, we compared the entire transcriptome of the Ercc1-/- mouse liver to that of wildtype littermates at the age of 15 days, when the Ercc1-/- mice reached their maximal weight and had symptoms of progeria, yet overall pathol...
ORGANISM(S): Mus musculus 
2006-12-21 | E-MEXP-834 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of liver from wild type mice of different ages to determine whether gene expression changes in naturally aged mice overlap with those from DNA repair deficient mice
To investigate whether and to which extent the gene expression changes in DNA repair deficient mice (i.e. Csbm/m/Xpa-/- and Ercc1-/-) overlap with those observed in a natural aged liver, we sought to compare the full mouse liver transcriptome of adult 16-, 96- and 130-week old wt C57Bl/6J mice (n=4)...
ORGANISM(S): Mus musculus 
2006-12-21 | E-MEXP-839 | biostudies-arrayexpress
UnknownA rare human centenarian variant of SIRT6 enhances genome stability and interaction with Lamin A
Not available
S-SCDT-EMBOJ-2021-110393 | biostudies-other
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