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TranscriptomicsMPA and NQO studies (Sevilla)
RNA polymerases deal with obstacles during transcription elongation that need to be removed. One important type of hindrance consists of DNA lesions, which are removed by transcription-coupled repair (TCR). To improve our knowledge of transcription elongation and its coupling to TCR, we performed DN...
ORGANISM(S): Saccharomyces cerevisiae 
2008-12-29 | E-GEOD-11561 | biostudies-arrayexpress
TranscriptomicsTranscription profiling time series of fission yeast after selective inhibition of Mcs6 and Cdk9
Selective inhibition of S. pombe Mcs6, Cdk9, or both via bulky nucleotide analogue.
ORGANISM(S): Schizosaccharomyces pombe 
2009-03-30 | E-MEXP-1746 | biostudies-arrayexpress
TranscriptomicsA positive feedback loop links opposing functions of P-TEFb/Cdk9 and histone H2B mono-ubiquitylation to regulate transcript elongation in fission yeast
Transcript elongation by RNA polymerase II (RNAPII) is accompanied by conserved patterns of histone modification within transcribed regions, but it remains uncertain how these modifications influence, or are influenced by, properties of the elongation complex. Here we establish an intimate link betw...
ORGANISM(S): Schizosaccharomyces pombe 
2012-12-01 | E-GEOD-31070 | biostudies-arrayexpress
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