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TranscriptomicsmiRNA expression during in vitro mouse T cell activation (D011.10+ CD4 T cells)
Array of global miRNA expression during an in vivo effector and anergic T cell response 250 ng RNA isolated from mouse D011.10+ CD4 T cells, activated in vivo for 5 days
ORGANISM(S): Mus musculus 
2013-01-27 | E-GEOD-36607 | biostudies-arrayexpress
TranscriptomicsA mouse model of HIES reveals pro and anti-inflammatory functions of STAT3
Mutations of STAT3 underlie the autosomal dominant form of hyper-immunoglobulin E syndrome (HIES). STAT3 has critical roles in immune cells and thus, hematopoietic stem cell transplantation (HSCT), might be a reasonable therapeutic strategy in this disease. However, STAT3 also has critical function...
ORGANISM(S): Mus musculus 
2014-03-06 | E-GEOD-55607 | biostudies-arrayexpress
TranscriptomicsGenetic modification of STAT5 levels reveals dose-dependent and isoform-specific requirement for cell lineage progression and differentiation.
Two highly conserved transcription factors STAT5A and STAT5B play an identical role in the intracellular signaling pathway upon cytokine stimulation, while gene deletion experiments have revealed separable and overlapping functions of STAT5. This questions whether the phenotypic differences in the ...
ORGANISM(S): Mus musculus 
2012-04-30 | E-GEOD-29045 | biostudies-arrayexpress
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