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TranscriptomicsRegulatory role of glycerol in Candida albicans biofilm formation
Biofilm formation on medically implanted devices by Candida albicans poses a significant clinical challenge. Here we compared biofilm-associated gene expression in two clinical C. albicans isolates, SC5314 and WO-1, to identify shared gene regulatory responses that may be functionally relevant. Amon...
ORGANISM(S): Candida albicans 
2013-04-12 | E-GEOD-45141 | biostudies-arrayexpress
UnknownSafety and tolerability of oral lisdexamfetamine in adults with methamphetamine dependence: a phase-2 dose-escalation study.
Not available
S-EPMC8137170 | biostudies-literature
MetabolomicsGut microbiota and fermentation-derived branched chain hydroxy acids mediate health benefits of yogurt consumption in obese mice
Meta-analyses suggest that yogurt consumption reduces type 2 diabetes incidence in humans, but the molecular basis of these observations remains unknown. Here we show that dietary yogurt intake preserves whole-body glucose homeostasis and prevents hepatic insulin resistance and liver steatosis in a ...
2022-02-03 | MTBLS442 | MetaboLights
TranscriptomicsTranscriptomic analysis of vulvovaginal candidiasis identifies a role for the NLRP3 inflammasome
RNA-seq analysis of an in vivo murine model of vulvovaginal candidiasis Murine vaginas were infected with Candida albicans and harvested for RNA-seq analysis 3 days post-infection
ORGANISM(S): Mus musculus 
2015-04-11 | E-GEOD-67688 | biostudies-arrayexpress
TranscriptomicsTuberculosis alters immune-metabolic pathways resulting in perturbed IL-1 responses [Luminex]
Tuberculosis (TB) remains a major public health problem and we lack a comprehensive understanding of how Mycobacterium tuberculosis (M. tb) infection impacts host immune responses. We compared, at two timepoints, the induced immune response to TB antigen, BCG and IL-1β stimulation between latently M...
ORGANISM(S): Homo sapiens 
2022-11-05 | E-MTAB-12380 | biostudies-arrayexpress
ProteomicsTuberculosis alters immune-metabolic pathways resulting in perturbed IL-1 responses [metabolomics]
Tuberculosis (TB) remains a major public health problem and we lack a comprehensive understanding of how Mycobacterium tuberculosis (M. tb) infection impacts host immune responses. We compared, at two timepoints, the induced immune response to TB antigen, BCG and IL-1β stimulation between latently M...
ORGANISM(S): Homo sapiens 
2022-11-05 | E-MTAB-12381 | biostudies-arrayexpress
TranscriptomicsTuberculosis alters immune-metabolic pathways resulting in perturbed IL-1 responses
Tuberculosis (TB) remains a major public health problem and we lack a comprehensive understanding of how Mycobacterium tuberculosis (M. tb) infection impacts host immune responses. We compared, at two timepoints, the induced immune response to TB antigen, BCG and IL-1β stimulation between latently M...
ORGANISM(S): Homo sapiens 
2022-11-05 | E-MTAB-12379 | biostudies-arrayexpress
TranscriptomicsBulk RNAseq of caudal fin regeneration in 24 hours post-amputation blastemas from zebrafish treated with the bioactive extract of the microalga Skeletonema costatum.
Adult Zebrafish (Danio rerio, 3 months old) were subjected to caudal fin amputation and exposed for 24 hours to either the ethanolic extract from the microalga Skeletonema costatum or its vehicle (ethanol 0.1 %) via waterborne exposure. At 24 hours post-amputation, fish were sacrificed. Regenerated ...
ORGANISM(S): Danio rerio 
2025-12-30 | E-MTAB-14677 | biostudies-arrayexpress
Unknownα-Synuclein and ALPS motifs are membrane curvature sensors whose contrasting chemistry mediates selective vesicle binding
Not available
S-JCBD-201011118 | bioimages
TranscriptomicsThe transcriptional regulator Cas5 influences the susceptibility of Candida albicans to Fluconazole.
Azole antifungal agents such as fluconazole exhibit fungistatic activity against Candida albicans. Strategies to enhance azole antifungal activity would be therapeutically appealing. In an effort to identify transcriptional pathways that influence fluconazole susceptibility, we sought to identify ...
ORGANISM(S): Candida albicans 
2014-05-24 | E-GEOD-57930 | biostudies-arrayexpress
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