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UnknownClassifying human promoters by occupancy patterns identifies recurring sequence elements, combinatorial binding, and spatial interactions.
Not available
S-EPMC6238301 | biostudies-literature
TranscriptomicsTranscription profiling of Arabidopsis development -AtGenExpress data set
This experiment is the result of normalizing the data previously submitted to ArrayExpress with the accession number E-AFMX-9.
ORGANISM(S): Arabidopsis thaliana 
2005-05-01 | E-TABM-17 | biostudies-arrayexpress
TranscriptomicsLinking aberrant chromatin features in chronic lymphocytic leukemia to deregulated transcription factor networks
In chronic lymphocytic leukemia (CLL) a diverse set of genetic mutations is embedded in a deregulated epigenetic landscape that drives cancerogenesis. To elucidate the role of aberrant chromatin features, we mapped DNA methylation, 7 histone modifications, nucleosome positions, chromatin accessibili...
ORGANISM(S): Homo sapiens 
2019-05-22 | GSE113336 | GEO
TranscriptomicsCircularized chromosome conformation capture (4C-seq) in A549 and U2OS cells stably expressing rat GR
To investigate the interaction landscape at the GILZ locus we performed 4C-seq in A549 (ATCC CCL-185) and U2OS cells stably expressing rat GR (Rogatsky et al. , Mol Cell Biol, 1997. 17(6): p. 3181-93.) upon hormone treatment (1.5 h, 1 M dexamethasone). Experiments were performed in two biological re...
ORGANISM(S): Homo sapiens 
2018-04-12 | E-MTAB-5350 | biostudies-arrayexpress
TranscriptomicsTranscription profling of human neuroblastoma samples to construct, validate and evalute a gene expression based classification of outcome of treatment
This set of 320 profiles was utilized to construct, validate and evaluate a gene-expression based classifier of outcome of neuroblastoma patients
ORGANISM(S): Homo sapiens 
2009-02-17 | E-TABM-38 | biostudies-arrayexpress
UnknownCorrespondence analysis applied to microarray data.
Not available
S-EPMC58552 | biostudies-literature
ProteomicsPreparation of tirapazamine-resistant hepatoma cell line
The aim of the project was to obtain murine hepatoma MH22a [1] cell subline, resistant to anticancer agent 3-amino-1,2,4-benzotriazine-1,4-dioxide (tirapazamine, TPZ), and examine the changes of the protein expression as compared with parental cells, with the main emphasis on the changes of redox pr...
ORGANISM(S): Mus musculus (Mouse) 
2023-05-10 | PXD039876 | Pride
Tirapazamine  hepatoma  resistance 
GenomicsGenome-wide profiling of H3K27ac (ChIP-seq) in IMR90 cells
To determine the genome-wide pattern of H3K27ac in IMR90 (ATCC CCL-186) cells we performed ChIP-seq upon hormone treatment (1.5 h, 1 M dexamethasone).
ORGANISM(S): Homo sapiens 
2018-04-12 | E-MTAB-5355 | biostudies-arrayexpress
GenomicsGlucocorticoid receptor profiling in IMR90,K562 and U2OS (ChIP-seq)
To identify the sequences responsible for recruitment of Glucocorticoid receptor (GR) to individual loci, we performed ChIP-seq and ChIP-exo that combines chromatin immunoprecipitation with an exonuclease digestion step. We performed these experiments in three cell lines : IMR90 (ATTC:CCL-186), U2O...
ORGANISM(S): Homo sapiens 
2015-02-25 | E-MTAB-2955 | biostudies-arrayexpress
GenomicsGenome-wide profiling of CTCF binding (ChIP-seq) in A549 and U2OS cells
To identify genome-wide CCCTC binding factor (CTCF)-binding in A549 (ATCC CCL-185) and U2OS cells stably expressing rat GR (Rogatsky et al. , Mol Cell Biol, 1997. 17(6): p. 3181-93.) we performed ChIP-seq experiments upon hormone treatment (1.5 h, 1 M dexamethasone).
ORGANISM(S): Homo sapiens 
2018-04-12 | E-MTAB-5352 | biostudies-arrayexpress
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