Mimivirus is a well-studied member of the family Mimiviridae which are ubiquitous in the environment. It is a fully cytoplasmic GV which is internalized into the host cell by phagocytosis. The acidic compartment of the phagosome, likely in conjugation with other unknown signals, triggers the opening...
The parental DG75 cell line is EBV negative and cannot express the viral BZLF1 protein, thus, this set of experiments served as a negative control. After ChIP, peaks were identified in both the human and viral (EBV (Human Herpesvirus 4) genome KF717093.1) genome. Only few peaks were identified. Expe...