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Obesity has been linked to lower mitochondrial metabolism in skeletal muscle. Weight loss yields many metabolic advantages, yet the effect of bariatric surgery versus caloric restriction on skeletal muscle mitochondrial metabolism and proteome remains to be elucidated.
ORGANISM(S): Homo sapiens (Human) 
2025-11-10 | PXD061410 | Pride
Brown fat generates heat via the mitochondrial uncoupling protein UCP1, defending against hypothermia and obesity. Recent data suggest that there are two distinct types of brown fat: classical brown fat derived from a myf-5 cellular lineage and UCP1-positive cells that emerge in white fat from a non...
ORGANISM(S): Mus musculus 
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