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ProteomicsEvaluation of the African swine fever virus-induced host shutoff using dynamic stable isotope labeling with amino acids in cell culture (SILAC)
African swine fever is a viral disease of swine caused by the African swine fever virus (ASFV). Currently, ASFV is a serious threat to the global pig industry. A viral strategy to undermine host cell response is to establish a global shutoff of host protein synthesis (virus-induced shutoff, vhs). He...
ORGANISM(S): Sus scrofa domesticus (domestic pig) 
2023-05-31 | PXD039806 | Pride
Silac African swine fever virus Virus host shutoff Vhs 
TranscriptomicsHerpes simplex host shutoff attenuates antiviral state
Herpes simplex virus mutants lacking the vhs gene are severely attenuated in animal models of pathogenesis and exhibit reduced growth in primary cell culture. As a result of these properties vhs-deleted virus have been proposed as live-attenuated viruses. Despite these findings and their implication...
ORGANISM(S): Mus musculus 
2008-04-03 | E-GEOD-10962 | biostudies-arrayexpress
TranscriptomicsvGPCR and lytic KSHV time course in TIME cells
TIME cells either expressing KSHV-RTA or KSHV-vGPCR alone, or TIME cells infected with KSHV and lytically reactivated with RTA for 6, 12, or 20 hours. Keywords = KSHV Keywords = host shutoff Keywords = vGPCR
ORGANISM(S): Homo sapiens 
2010-06-09 | E-GEOD-1406 | biostudies-arrayexpress
GenomicsEpstein-Barr virus induces host shutoff extensively via BGLF5-independent mechanisms [RNA-seq]
Epstein-Barr virus induces host shutoff extensively via BGLF5-independent mechanisms [RNA-seq]
PRJNA1132980 | ENA
no omics definedTranscription profiling of mouse fibroblast-like cells infected with mouse hepatitis virus
Effect of mouse hepatitis virus strain A59 replication on gene expression and mRNA stability in LR cells
ORGANISM(S): Mus musculus 
2007-11-13 | E-MEXP-895 | biostudies-arrayexpress
TranscriptomicsEpstein-Barr virus induces host shutoff extensively via BGLF5-independent mechanisms [RNA-seq]
This study characterizes the effects of Epstein-Barr virus (EBV) reactivation on the host and virus transcriptomes. For this work, a dual-fluorescent lytic reporter (DFLR) EBV was constructed based on the M81 EBV strain and used to transform primary B cells into lymphoblastoid cell lines (LCL). Depo...
ORGANISM(S): Homo sapiens 
2024-07-08 | GSE271717 | GEO
GenomicsEpstein-Barr virus reactivation induces divergent abortive, reprogrammed, and host shutoff states by lytic progression
Epstein-Barr virus reactivation induces divergent abortive, reprogrammed, and host shutoff states by lytic progression
PRJNA1138692 | ENA
ProteomicsmRNA 3’UTR lengthening by alternative polyadenylation attenuates inflammatory responses and correlates with virulence of Influenza A virus
Alternative polyadenylation (APA) leading to changes of mRNA 3’UTRs has been associated to numerous pathologies but its molecular origin and functional consequences often remain enigmatic. We show that all Influenza A virus (IAV) strains cause APA of host transcripts and mapped the effect to a dru...
ORGANISM(S): Homo sapiens (Human) 
2023-07-12 | PXD040456 | Pride
Iav Ns1 Semliki forest virus Pr8 Sfv Influenza a 
TranscriptomicsSimultaneous and systematic analysis of cellular and viral gene expression during Enterovirus 71-induced host shutoff
Enterovirus 71 (EV71) infection causes a profound shutoff of cellular protein synthesis. Deep RNA-sequencing and ribosome profiling were employed to systematically analyze messenger RNA and ribosome-protected RNA in EV71-infected rhabdomyosarcoma cells at progressive time points following infection....
ORGANISM(S): Homo sapiens 
2018-05-03 | GSE103308 | GEO
UnknownRibosome Profiling Reveals Translational Upregulation of Cellular Oxidative Phosphorylation mRNAs during Vaccinia Virus-Induced Host Shutoff.
Not available
S-EPMC5309933 | biostudies-literature
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