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ProteomicsProtein turnover dynamics of IAV-infected HeLa cells
The abundance of a protein is defined by its continuous synthesis and degradation, a process known as protein turnover. Here, we systematically profiled the turnover of proteins in influenza A virus (IAV) infected cells using a pulse-chase SILAC-based approach combined with downstream statistical mo...
ORGANISM(S): Homo sapiens (Human) 
2025-04-09 | PXD047063 | Pride
Iav Pulse-chase Silac Hela Protein turnover Lc-msms 
ProteomicsStrain- and cell type-specific influenza A virus (IAV)-host protein-protein interaction (PPI) network identified by affinity purification-mass spectrometry (AP-MS)
Influenza A Virus (IAV) is a recurring respiratory virus with antiviral therapies of limited use. Understanding host proteins essential for IAV infection can identify targets for alternative host-directed therapies (HDTs). Using affinity purification-mass spectrometry and global phosphoproteomic and...
ORGANISM(S): Homo sapiens (Human) 
2023-07-25 | PXD036077 | Pride
Virus-host H5n1 Human Ppi H1n1 A549 Nhbe H3n2 Thp-1 Ap-ms Influenza a virus 
ProteomicsGlobal Protein Abundance and Phosphorylation Analyses of Influenza A Virus (IAV)-Infected Human Cells
Influenza A Virus (IAV) is a recurring respiratory virus with antiviral therapies of limited use. Understanding host proteins essential for IAV infection can identify targets for alternative host-directed therapies (HDTs). Using affinity purification-mass spectrometry and global phosphoproteomic and...
ORGANISM(S): Homo sapiens (Human) 
2023-07-25 | PXD035900 | Pride
Human H5n1 H1n1 Protein abundance Phosphorylation Nhbe H3n2 Thp-1 Infection Influenza a virus 
ProteomicsProteome of GPKOW depleted cells with IAV infection, IFN or PPP-RNA treatment
The abundance of a protein is defined by its continuous synthesis and degradation, a process known as protein turnover. Here, we systematically profiled the turnover of proteins in influenza A virus (IAV) infected cells using a pulse-chase SILAC-based approach combined with downstream statistical mo...
ORGANISM(S): Homo sapiens (Human) 
2025-04-09 | PXD047060 | Pride
Lc-msms Innate immunity Gpkow Hela A549 
GenomicsHuman CMV-specific vs IAV-specific CD8 T cells
Human CMV-specific vs IAV-specific CD8 T cells
PRJNA718851 | ENA
GenomicsHuman CMV-specific vs IAV-specific CD8 TCM cells
Human CMV-specific vs IAV-specific CD8 TCM cells
PRJNA823760 | ENA
MetabolomicsMulti-omics association analysis reveals interactions between the oropharyngeal microbiome and the metabolome in pediatric patients with influenza A virus pneumonia.
Children are at high risk for influenza A virus (IAV) infections, which can develop into severe illnesses. However, little is known about interactions between the microbiome and respiratory tract metabolites and their impact on the development of IAV pneumonia in children. Using a combination of liq...
2024-09-25 | MTBLS4816 | MetaboLights
TranscriptomicsInfluenza infection rewires energy metabolism and induces browning features in adipose cells and tissues
C57BL/6 mice were intranasally inoculated with a sublethal dose of H3N2 Influenza A virus (IAV) or with PBS (mock). At 7 days post-infection (7 dpi, corresponding to the peak inflammatory response in the lungs), IAV-infected and non-infected mice were sacrified and inguinal (SCAT) and visceral (i.e....
ORGANISM(S): Mus musculus 
2020-05-16 | E-MTAB-7984 | biostudies-arrayexpress
GenomicsArhgdia regulates disease tolerance in IAV-infected epithelial cells
Arhgdia regulates disease tolerance in IAV-infected epithelial cells
PRJNA795157 | ENA
GenomicsAirway Microfold (M) Cells Emerge in the Post-IAV Lung
Airway Microfold (M) Cells Emerge in the Post-IAV Lung
PRJNA1022055 | ENA
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