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TranscriptomicsLung expression data from highly pathogenic H5N1 virus infected and uninfected mice
Susceptible and Resistant mouse strain, e.g. DBA/2J and C57BL/6J respectively, were inoculated with a highly pathogenic H5N1 influenza A virus (A/Hong Kong/213/2003) for 72 hours. Differences in expression were analyzed and use to identify candidate genes and pathways that contributed to the differe...
ORGANISM(S): Mus musculus 
2015-01-08 | E-GEOD-64750 | biostudies-arrayexpress
TranscriptomicsTranscriptome analysis of lungs from six different mouse strains after infection with highly pathogenic H5N1 influenza A virus [set 2]
Susceptible (DBA/2J, 129/SvImJ, A/J) and Resistant (SM/J, C57BL/6J, Balb/cJ) mouse strain were inoculated with a highly pathogenic H5N1 influenza A virus (A/Hong Kong/213/2003) for 72 hours or not infected (control animals). Differences in expression were analyzed and used to identify candidate gen...
ORGANISM(S): Mus musculus 
2015-01-09 | E-GEOD-64799 | biostudies-arrayexpress
TranscriptomicsTranscriptome analysis of lungs from six different mouse strains after infection with highly pathogenic H5N1 influenza A virus [set 1]
Susceptible (DBA/2J, 129/SvImJ, A/J) and Resistant (SM/J, C57BL/6J, Balb/cJ) mouse strain were inoculated with a highly pathogenic H5N1 influenza A virus (A/Hong Kong/213/2003) for 24 and 168 hours. Uninfected control animals were included. Differences in expression were analyzed and used to identi...
ORGANISM(S): Mus musculus 
2015-01-09 | E-GEOD-64798 | biostudies-arrayexpress
TranscriptomicsHost Regulatory Network Response to Infection with Highly Pathogenic H5N1 Avian Influenza Virus
Over the last decade, more than half of humans infected with highly pathogenic avian influenza (HPAI) H5N1 viruses have died, and yet virus-induced host signaling has yet to be clearly elucidated. Airway epithelia are known to produce inflammatory mediators that contribute to HPAI H5N1-mediated pat...
ORGANISM(S): Homo sapiens 
2011-09-01 | E-GEOD-28166 | biostudies-arrayexpress
TranscriptomicsLungs of ferrets infected with either an H3N2 or H5N1 subtype of influenza A virus.
A global genomics approach was used to identify patterns of immune dysregulation during H5N1 influenza virus infection as the host response, in particular hyperchemokinemia, is thought to contribute to the extreme pathology associated with this disease. Keywords: time course Ferrets were inoculated ...
ORGANISM(S): Mustela putorius furo 
2010-05-15 | E-GEOD-9606 | biostudies-arrayexpress
TranscriptomicsInsights into responses of human astrocytes to H5N1 infection by transcriptional analysis
Increasing evidence demonstrates influenza virus can not only affect the respiratory system, but also infect CNS and lead to CNS disorder and encephalopathy and encephalitis. Astrocytes are the most abundant cells in the CNS, which are capable of producing cytokines and neurotrophic factors and are ...
ORGANISM(S): Homo sapiens 
2016-01-04 | E-GEOD-66597 | biostudies-arrayexpress
TranscriptomicsGene expression data from lung of mice infected with H5N1 or H1N1 virus
To find the different host response during H5N1 and H1N1 infection, we have employed whole genome microarray expression profiling as a discovery platform to identify genes differentially expressed in mouse lungs infected by H5N1 and H1N1 virus. BALB/c mice were infected with live H5N1 virus , live H...
ORGANISM(S): Mus musculus 
2016-01-12 | E-GEOD-76719 | biostudies-arrayexpress
GenomicsInfluenza A virus strain:H5N1
H5N1 Influenza A virus Raw sequence reads
PRJNA381590 | ENA
GenomicsInfluenza A virus strain:H5N1
Influenza A virus strain:H5N1 Genome sequencing
PRJNA248762 | ENA
TranscriptomicsExpression data of influenza A infected human macrophages
Human disease caused by highly pathogenic avian influenza (HPAI) H5N1 can lead to a rapidly progressive viral pneumonia leading to acute respiratory distress syndrome. There is increasing evidence suggests a role for virus-induced cytokine dysregulation in contributing to the pathogenesis of human H...
ORGANISM(S): Homo sapiens 
2009-10-31 | E-GEOD-18816 | biostudies-arrayexpress
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