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TranscriptomicsTranscription profiling of four human prostate cancer cell lines and seven prostate cancer xenografts
Gene expression profiling of four prostate cancer cell lines and seven prostate cancer xenografts. The experiment was done to see which genes were over- or underexpressed in the samples. The results were combined with aCGH results of the same samples (experiment prostate cancer CGH) to see, whether ...
ORGANISM(S): Homo sapiens 
2005-12-30 | E-MEXP-336 | biostudies-arrayexpress
TranscriptomicsComparative genomic hybridization of 5 human prostate cancer cell lines and 13 prostate cancer xenografts to create genomic profiles of copy number alterations
Array-CGH was done with 5 prostate cancer cell lines and 13 prostate cancer xenografts to create genomic profiles of copy number alterations. The profiles were used to identify common alterations and define minimal regions of copy number changes. A normal female to normal male hybridisation was done...
ORGANISM(S): Homo sapiens 
2005-12-31 | E-MEXP-335 | biostudies-arrayexpress
TranscriptomicsRNA-seq of dihydrotestosterone (DHT) stimulated prostate epithelial cell lines RWPE-1-Ctrl, RWPE-1-AR and prostate cancer cell lines LNCaP-pcDNA3.1 and LNCaP-Arhi
RNA-sequencing from RWPE-Ctrl (empty vector control), RWPE-1-AR (transduced with androgen receptor cDNA), LNCaP-pcDNA3.1 (empty vector control), and LNCaP-ARhi (transfected with androgen receptor cDNA) cells treated with 0, 1, 10, or 100 nM DHT for 4 hours before RNA extraction. Biological triplicat...
ORGANISM(S): Homo sapiens 
2026-07-31 | E-MTAB-15758 | biostudies-arrayexpress
TranscriptomicsATAC-seq of dihydrotestosterone (DHT) stimulated prostate epithelial cell lines RWPE-1-Ctrl, RWPE-1-AR and prostate cancer cell lines LNCaP-pcDNA3.1 and LNCaP-Arhi
ATAC-sequencing from RWPE-Ctrl (empty vector control), RWPE-1-AR (transduced with androgen receptor cDNA), LNCaP-pcDNA3.1 (empty vector control), and LNCaP-ARhi (transfected with androgen receptor cDNA) cells treated with 0, 1, 10, or 100 nM DHT for 2 hours before nuclei isolation. Biological duplic...
ORGANISM(S): Homo sapiens 
2026-07-31 | E-MTAB-15731 | biostudies-arrayexpress
no omics definedTranscription profiling of human prostate cancer cells over-expressing androgen receptor following dihydrotestosterone treament
dose and time dependent responses of dihydrotestosterone in androgen receptor over-expressing prostate cancer cells.
ORGANISM(S): Homo sapiens 
2009-10-09 | E-MEXP-2286 | biostudies-arrayexpress
TranscriptomicsMicroRNA profiling of human prostate cancer cell lines, xenografts and tumor samples
miRNA expression profiling in 6 prostate cancer cell lines, 9 prostate cancer xenografts, and 13 clinical prostate tumor samples
ORGANISM(S): Homo sapiens 
2007-08-03 | E-MEXP-1058 | biostudies-arrayexpress
GenomicsOverexpression of androgen receptor enhances the binding of the receptor to the chromatin in prostate cancer
Androgen receptor (AR) is overexpressed in the majority of castration-resistant prostate cancers (CRPCs). Our goal was to study the effect of AR overexpression on the chromatin binding of the receptor and to identify AR target genes that may be important in the emergence of CRPC. We have established...
ORGANISM(S): Homo sapiens 
2013-06-27 | E-GEOD-48308 | biostudies-arrayexpress
GenomicsOrigins and functional consequence of somatic mitochondrial DNA mutations
Recent sequencing studies have extensively explored the somatic alterations present in the nuclear genomes of cancers. Although mitochondria control energy metabolism and apoptosis, the origins and impact of cancer-associated mutations in mitochondrial DNA (mtDNA) are unclear. Here, we analysed soma...
EGAS00001000968 | EGA
Genomicsena-DATASET-BioMediTech-01-01-2016-11:07:07:068-452 - samples
We report the first combined analysis of whole genome sequence, detailed clinical history, and transcriptome sequence of multiple prostate cancer metastases in a single patient (A21). Whole genome and transcriptome sequence was obtained from 9 anatomically separate metastases, and targeted DNA sequ...
EGAD00001001869 | EGA
GenomicsIntegrated clinical, whole genome, and transcriptome analysis of multisampled lethal metastatic prostate cancer
We report the first combined analysis of whole genome sequence, detailed clinical history, and transcriptome sequence of multiple prostate cancer metastases in a single patient (A21). Whole genome and transcriptome sequence was obtained from 9 anatomically separate metastases, and targeted DNA sequ...
EGAS00001001659 | EGA
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