Sort   by:  
 Page size 
TranscriptomicsRNA-seq of murine CD4 T cells after pentanoate treatment compared to untreated control
To analyse the influence of pentanoate on the differentiation of naive CD4 T cells under Th17 inducing conditions, murine CD4 T cells were isolated from spleen and lymphnodes of FIR/TIGER mice (IL-10 (GFP) - Foxp3 (RFP) - Reporter mice). The T cells were kept for 3 days under Th17 inducing condition...
ORGANISM(S): Mus musculus 
2019-01-15 | E-MTAB-6114 | biostudies-arrayexpress
TranscriptomicsRNA-seq of murine spleen B-cells after pentanoate treatment compared to untreated control
We tested the influence of pentanoate on B cells by treatment of CpG-stimulated B cells in vitro. We isolated naive B cells from FIR/TIGER mice (IL-10 (GFP) - Foxp3 (RFP) - Reporter mice) from spleen. Cells were cultured in presence of 5 µg/ml CpG 2395. 24h after CpG-stimulation, B cells were treate...
ORGANISM(S): Mus musculus 
2019-01-15 | E-MTAB-6115 | biostudies-arrayexpress
TranscriptomicsFood protein-induced activation and death of CD4+ Helios+ Foxp3- T cells is required for IL-10 production and intestinal homeostasis
The impact of dietary proteins on homeostasis and immune function of the intestine is poorly understood. We here show that physiological uptake of dietary proteins induced an activated, CD4+CD44+Helios+ T cell population, predominantly in Peyer's patches (PP). These cells are distinct from Foxp3+reg...
ORGANISM(S): Mus musculus 
2016-07-01 | E-GEOD-66938 | biostudies-arrayexpress
UnknownThe short-chain fatty acid pentanoate suppresses autoimmunity by modulating the metabolic-epigenetic crosstalk in lymphocytes.
Not available
S-EPMC6377655 | biostudies-literature
UnknownLactate induces metabolic and epigenetic reprogramming of pro-inflammatory Th17 cells
Not available
S-SCDT-EMBOR-2022-54685V1 | biostudies-other
Sort   by:  
 Page size