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Background & Aims: Immune-mediated drug-induced liver injury (DILI) is triggered or exacerbated by the immune system mounting an attack against the drug or its metabolites. The array of in vitro assays for evaluating intrinsic immunogenicity of drugs is limited, highlighting a significant gap in eff...
ORGANISM(S): Homo sapiens (Human) 
2026-08-13 | PXD075232 | Pride
Background. Dyslipidemia is associated with chronic kidney disease (CKD). It has been shown that inhibition of β-oxidation and lipid accumulation are common threats in the onset of kidney injury and conducive to fibrosis. We characterized the S-acylated proteome of kidneys from mice with diet-induce...
ORGANISM(S): Mus musculus (Mouse) 
2025-03-21 | PXD052634 | Pride
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