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TranscriptomicsExpression Profiles of Monozygotic Twin
The expression level for 15 887 transcripts in lymphoblastoid cell lines from 19 monozygotic twin pairs (10 male, 9 female) were analysed for the effects of genotype and sex. On an average, the effect of twin pairs explained 31% of the variance in normalized gene expression levels, consistent with p...
ORGANISM(S): Homo sapiens 
2008-03-30 | E-GEOD-7624 | biostudies-arrayexpress
TranscriptomicsNeonatal DNA methylation profile in humans is specified by a complex interplay between intrauterine environmental/ genetic factors subject to tissue-specific influence
Comparison between groups of monozygotic (MZ) and dizygotic (DZ) twins enables an estimation of the relative contribution of genetic, shared and non-shared environmental factors to phenotypic variability. Using DNA methylation profiling of ~20,000 CpG sites as a phenotype, we have examined discordan...
ORGANISM(S): Homo sapiens 
2012-07-17 | E-GEOD-36642 | biostudies-arrayexpress
GenomicsLBC_Methylation - samples
DNA methylation data using Illumina 450K
EGAD00010000604 | EGA
GenomicsDNA methylation repeatability in the Lothian Birth Cohorts of 1921 and 1936.
The repeatability of longitudinal measures of whole blood DNA methylation (obtained using the Illumina 450k chip) was assessed in two cohorts of ageing. The Lothian Birth Cohort of 1921 and the Lothian Birth Cohort of 1936. Data were collected at ages 70, 73, and 76 (LBC1936) and 79, 87, 90 (LBC1921...
EGAS00001000910 | EGA
GenomicsLongitudinal DNA methylation in the Lothian Birth Cohorts of 1921 and 1936
Data Access Committee EGAC00001000218
EGAC00001000218 | EGA
GenomicsXXX
GenomeEUtwin control samples
EGAD00000000043 | EGA
GenomicsGeographical structure and differential natural selection among North European populations
European populations and epidemiological cohorts are of special significance in the current era of genomic research aiming to characterize the background of common human diseases. The genome sequence, detailed information of genetic variations between individuals, high-throughput molecular technolog...
EGAS00000000033 | EGA
GenomicsGenomeEUtwin Data Access Committee
Access to data generated by the GenomeEUtwin is available by emailing application to the data access committee and will be granted to qualified investigators for appropriate use.
EGAC00000000007 | EGA
UnknownFamily-GWAS reveals effects of environment and mating on genetic associations.
Not available
S-EPMC12633112 | biostudies-literature
UnknownWhole-exome sequencing in amyotrophic lateral sclerosis suggests NEK1 is a risk gene in Chinese.
Not available
S-EPMC5693798 | biostudies-literature
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