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ProteomicsProteomic Analysis Reveals the Mechanisms Underlying Ischemic Stroke Induced by Vitamin B12 Deficiency
Recruit patients with first-ever acute ischemic stroke (AIS) and classify them into two study groups based on the presence or absence of vitamin B12 deficiency, while also including a matched healthy control group. Utilize 4D-DIA proteomics technology to analyze the protein expression profiles and i...
ORGANISM(S): Homo sapiens (Human) 
2026-02-20 | PXD062264 | Pride
Vitamin b12 deficiency Proteomic Ischemic stroke 
TranscriptomicsFolate and vitamin B12 imbalance induces endoplasmic reticulum stress and cholesterol biosynthesis gene expression in human adipocytes
Rationale: Low B12 has been shown to play an important role in the prediction of metabolic risk, but its significance and mechanism in the development of adiposity and adipose tissue dysfunction is largely unknown. Objective: To investigate the role of B12 and folic acid in the development of adipo...
ORGANISM(S): Homo sapiens 
2012-12-30 | E-GEOD-43166 | biostudies-arrayexpress
TranscriptomicsTranscriptomics of rat born to dams fed a diet deficient in methyl group donors
It is clearly established that the maternal diet during pregnancy can induce physiological and metabolic adaptations in the developing fetus which determine its susceptibility later in life to develop diabetes, obesity... The molecular and genomic mechanisms underlying the programming of the metabol...
ORGANISM(S): Rattus norvegicus 
2015-06-22 | E-GEOD-59039 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of blood cells from rats fed a folate deficient diet vs fed a normal diet for 28 days
Wistar Kyoto, inbred male rats (M & B, Ry, Denmark) were randomized and fed a semisynthetic pellet diet deficient in folate (TD350, Harland, Madison, Wisconsin, USA) or an identical diet with a normal amount of folate (TD351, Harland). Special analyses were performed to establish the content of Meth...
ORGANISM(S): Rattus norvegicus 
2005-08-01 | E-MEXP-154 | biostudies-arrayexpress
TranscriptomicsEffects of Intramuscular Administration of Folic Acid and Vitamin B12 on Granulosa Cells Gene Expression in Postpartum Dairy Cow
The fertility of dairy cows is challenged during early lactation and better nutritional strategies need to be developed to address this issue. Combined supplementation of folic acid and vitamin B12 improves energy metabolism in the dairy cow during early lactation. Therefore, the present study was u...
ORGANISM(S): Bos taurus 
2015-09-15 | E-GEOD-72038 | biostudies-arrayexpress
GenomicsB12 in murine colitis
Vitamin B12 Deficiency Alters the Gut Microbiota in a Murine Model of Colitis
PRJEB37474 | ENA
UnknownPseudoparalysis in Infantile Vitamin B12 Deficiency.
Not available
S-EPMC12798916 | biostudies-literature
UnknownTranscobalamin deficiency: vitamin B12 deficiency with normal serum B12 levels.
Not available
S-EPMC6827761 | biostudies-literature
TranscriptomicsEpigenomics of rat born to dams fed a diet deficient in methyl group donors (MDD)
It is clearly established that the maternal diet during pregnancy can induce physiological and metabolic adaptations in the developing fetus which determine its susceptibility later in life to develop diabetes, obesity... The molecular and genomic mechanisms underlying the programming of the metabol...
ORGANISM(S): Rattus norvegicus 
2015-06-22 | E-GEOD-59191 | biostudies-arrayexpress
UnknownMaternal vitamin B12 deficiency and perinatal outcomes in southern India.
Not available
S-EPMC8023483 | biostudies-literature
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