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Lack of VMP1 Impairs Hepatic Lipoprotein Secretion and Promotes Nonalcoholic Steatohepatitis
The study aims at identifying the interactome of T. gondii VMP1.
ORGANISM(S): Toxoplasma gondii RH 
2025-10-15 | PXD056007 | Pride
VMP1 restricts NLRP3 inflammasome activation through its modulation of SERCA activity and autophagy
The purpose of this study is to identify the differential transcriptome profiles in WT and hepatocyte deletion of VMP1 mouse livers. Floxed VMP1 mice were intravenously injected with AAV8-TBG-null or AAV8-TBG-cre for 2 weeks. Liver mRNA were extracted and performed for Nextseq analysis in triplicate...
ORGANISM(S): Mus musculus 
2022-04-20 | GSE186642 | GEO
To investigate the effect of VMP1 deletion on gene expression in either untreated or LPS and ATP treated human differentiated THP-1 cells. CRISPR-Cas9 technology was used to generate stable knockout cell lines. We then performed an RNA-Seq experiment to assess gene expression changes between untreat...
ORGANISM(S): Homo sapiens 
2023-10-12 | GSE215432 | GEO
Renal tubular VMP1 protects against acute kidney injury via facilitating autophagic flux
Acute kidney injury (AKI) is intricately linked to autophagy. Our study investigates the pivotal role of the autophagy-associated protein VMP1 in the pathogenesis and progression of AKI.
ORGANISM(S): Homo sapiens 
2026-01-12 | GSE277267 | GEO
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