Sort   by:  
 Page size 
ProteomicsProteomic Profiling of PTEN Inhibition on Periodontal Ligament Stem Cells
: Phosphatase and tensin homolog (PTEN) is a critical regulator of cell proliferation, differentiation, and inflammatory balance. However, its downstream proteomic effects in periodontal ligament stem cells (PDLSCs) remain poorly understood. This study aimed to elucidate the proteomic alterations in...
ORGANISM(S): Homo sapiens (Human) 
2026-03-30 | PXD074161 | Pride
Mesenchymal stem cells Vo-ohpic Periodontal regeneration Mapk cascade Proteomics Pten inhibitor 
TranscriptomicsThe effect of PTEN inhibitor on Periodontal ligament cells
Objective: Phosphatase and Tensin Homolog (PTEN) act as a negative regulator of the phosphatidylinositol-3-kinase (PI3k)/Akt pathway, which is involved in cell growth, cell proliferation, differentiation, and survival signaling. This study aimed to investigate the effects of VO-OHpic, a PTEN inhibit...
ORGANISM(S): Homo sapiens 
2025-04-20 | GSE295018 | GEO
UnknownA PTEN inhibitor displays preclinical activity against hepatocarcinoma cells.
Not available
S-EPMC5056616 | biostudies-literature
UnknownMiR-21 promotes pterygium cell proliferation through the PTEN/AKT pathway.
Not available
S-EPMC6416795 | biostudies-literature
UnknownPTEN Inhibitor Treatment Lowers Muscle Plasma Membrane Damage and Enhances Muscle ECM Homeostasis after High-Intensity Eccentric Exercise in Mice.
Not available
S-EPMC10298298 | biostudies-literature
GenomicsThe effect of PTEN inhibitor on Periodontal ligament cells
The effect of PTEN inhibitor on Periodontal ligament cells
PRJNA1252465 | ENA
UnknownGlycolysis regulates palatal mesenchyme proliferation through Pten-Glut1 axis via Pten classical and non-classical pathways.
Not available
S-EPMC11868302 | biostudies-literature
UnknownFabricating Microfluidic Co-Cultures of Immortalized Cell Lines Uncovers Robust Design Principles for the Simultaneous Formation of Patterned, Vascularized, and Stem Cell-Derived Adipose Tissue.
Not available
S-EPMC12366273 | biostudies-literature
UnknownMaspin is a PTEN-Upregulated and p53-Upregulated Tumor Suppressor Gene and Acts as an HDAC1 Inhibitor in Human Bladder Cancer.
Not available
S-EPMC7016534 | biostudies-literature
UnknownMicroRNA-1297 suppressed the Akt/GSK3β signaling pathway and stimulated neural apoptosis in an in vivo sevoflurane exposure model.
Not available
S-EPMC8044581 | biostudies-literature
Sort   by:  
 Page size