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ProteomicsA porcine spectral assay library to quantify brain proteome by DIA-MS
The peptide-centric analysis requires spectral assay libraries that allow for the extraction of quantitative data in mass spectrometry-based methods, including data-independent acquisition (DIA), parallel reaction monitoring (PRM), or selected reaction monitoring (SRM). Such spectral libraries have ...
ORGANISM(S): Sus scrofa domesticus (domestic pig) 
2026-05-18 | PXD074603 | Pride
TranscriptomicsExpression data from fibroblasts, iPSCs and neurons with four copies of SNCA, and equivalent cell lines from an unaffected first degree relative
A major barrier to research on Parkinson’s disease (PD) is inaccessibility of diseased tissue for study. One solution is to derive induced pluripotent stem cells (iPSCs) from patients with PD and differentiate them into neurons affected by disease. We created an iPSC model of PD caused by triplicati...
ORGANISM(S): Homo sapiens 
2011-09-14 | E-GEOD-28365 | biostudies-arrayexpress
TranscriptomicsSNP data from genomic DNA from a subject, fibroblasts, iPSCs and neurons with four copies of SNCA, and genomic DNA from an unaffected first degree relative and equivalent cell lines
A major barrier to research on Parkinson’s disease (PD) is inaccessibility of diseased tissue for study. One solution is to derive induced pluripotent stem cells (iPSCs) from patients with PD and differentiate them into neurons affected by disease. We created an iPSC model of PD caused by triplicati...
ORGANISM(S): Homo sapiens 
2011-09-14 | E-GEOD-28366 | biostudies-arrayexpress
TranscriptomicsExpression data from Parkison's iPSCs with four copies of SNCA, and equivalent cell lines from an unaffected first degree relative
A major barrier to research on Parkinson’s disease (PD) is inaccessibility of diseased tissue for study. One solution is to derive induced pluripotent stem cells (iPSCs) from patients with PD and differentiate them into neurons affected by disease. We created an iPSC model of PD caused by triplicati...
ORGANISM(S): Homo sapiens 
2011-09-14 | E-GEOD-30792 | biostudies-arrayexpress
ProteomicsProteomic characterization of extracellular matrix (ECM) produced by human fibroblast activation protein (FAP)-positive pericyte-like cells and glioma cells
Fibroblast activation protein (FAP) is upregulated in most cancers and represents an emerging theranostic target in oncology. In glioblastoma (GBM), FAP is predominantly expressed in mesenchymal pericyte-like cells, which contribute to GBM progression by promoting angiogenesis and glioma cell prolif...
ORGANISM(S): Homo Sapiens 
PXD045057 | panorama
TranscriptomicsComparative transcriptomic analysis of in vivo and in vitro produced bovine 4-cell stage and 8-cell stage embryos
Pre-implantation embryos derived by in vitro fertilization differ in their developmental potential from embryos obtained in vivo. In order to characterize changes in gene expression profiles caused by in vitro culture environment, we employed microarray constructed from bovine embryo-specific cDNAs ...
ORGANISM(S): Bos taurus 
2011-01-31 | E-GEOD-24714 | biostudies-arrayexpress
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