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GenomicsGenome-wide maps of chromatin state in E12.5 mouse forelimbs
The chromatin state in developing body parts provides a zip code to cellular populations that direct their cell fates. We used antibodies for H3K4me3, H3K27me3 and Pol2, to identify the chromatin state signature of the mouse forelimb during mid-gestation, at embryonic day 12. The families of genes m...
ORGANISM(S): Mus musculus 
2015-02-20 | E-GEOD-49010 | biostudies-arrayexpress
UnknownLive in vivo imaging of Egr-1 promoter activity during neonatal development, liver regeneration and wound healing.
Not available
S-EPMC3120781 | biostudies-literature
TranscriptomicsTranscription profiling by array of mammospheres derived from tumors of mice harboring Wnt/Met signaling mutations treated Wnt and MET pathway inhibitors
The combined activation of Wnt/ß-catenin and MET/HGF is required for mammary cancer stem cell (MaCSC) maintenance. We generated mammospheres derived from tumors of mice harboring Wnt/Met signaling mutations on which we performed microarray analysis to evaluate gene expression signatures controlled b...
ORGANISM(S): Mus musculus 
2014-02-18 | E-GEOD-35899 | biostudies-arrayexpress
TranscriptomicsShp2 Signaling Suppresses Senescence in PyMT-induced Mammary Gland Cancer in Mice [Mouse430_2 array]
In this study, we have used techniques from cell biology, biochemistry, and genetics to investigate the role of the tyrosine phosphatase Shp2 in tumor cells of MMTV-PyMT mouse mammary glands. Genetic ablation or pharmacological inhibition of Shp2 induces senescence, as determined by the activation o...
ORGANISM(S): Mus musculus 
2015-03-06 | E-GEOD-50517 | biostudies-arrayexpress
TranscriptomicsShp2 Signaling Suppresses Senescence in PyMT-induced Mammary Gland Cancer in Mice [Mouse430A_2 array]
In this study, we have used techniques from cell biology, biochemistry, and genetics to investigate the role of the tyrosine phosphatase Shp2 in tumor cells of MMTV-PyMT mouse mammary glands. Genetic ablation or pharmacological inhibition of Shp2 induces senescence, as determined by the activation o...
ORGANISM(S): Mus musculus 
2015-03-06 | E-GEOD-50516 | biostudies-arrayexpress
UnknownKAT6B overexpression in mice causes aggression, anxiety, and epilepsy.
Not available
S-EPMC11904597 | biostudies-literature
UnknownVersatile strategy for homogeneous drying patterns of dispersed particles.
Not available
S-EPMC9126951 | biostudies-literature
ProteomicsMitochondrial damage drives T-cell immunometabolic paralysis after major surgery
Cytotoxic T cell (CTL) dysfunction is a key feature of immune paralysis following major surgery, significantly increasing the risk of severe nosocomial infections and contributing to elevated mortality in critically ill patients. The pathomechanisms of CTL dysfunction remain unclear. We report that ...
ORGANISM(S): Homo sapiens (Human) 
2025-12-09 | PXD060723 | Pride
UnknownAerobic endurance training to improve cognition and enhance recovery in schizophrenia: design and methodology of a multicenter randomized controlled trial.
Not available
S-EPMC8257533 | biostudies-literature
UnknownPredictors of adherence to exercise interventions in people with schizophrenia.
Not available
S-EPMC11362191 | biostudies-literature
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