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TranscriptomicsP493-6 treated with KJ-Pyr-9 and/or Doxycycline
In a fluorescence polarization screen for MYC-MAX interaction, we have identified a novel small molecule inhibitor of MYC, KJ-Pyr-9, from a Kröhnke pyridine library. The Kd of KJ-Pyr-9 for MYC in vitro is 6.5 ± 1.0 nM as determined by backscattering interferometry; KJ-Pyr-9 also interferes with MYC-...
ORGANISM(S): Homo sapiens 
2014-08-25 | E-GEOD-58168 | biostudies-arrayexpress
TranscriptomicsHigh weight differences between donor and recipient affect early kidney graft function -a role for IL-6 signaling
The frequency of delayed function of kidney transplants varies greatly and is associated with the quality of graft, donor age, and the duration of cold ischemia time. Body weight differences between donor and recipient can affect primary graft function. The underlying mechanism is poorly understood....
ORGANISM(S): Rattus norvegicus 
2010-04-08 | E-GEOD-15813 | biostudies-arrayexpress
UnknownAURORA A interacts with DICER and SETD2 to promote S-phase progression
Not available
S-SCDT-10_1038-S44319-026-00850-0 | biostudies-other
TranscriptomicsExpression data from mouse embryonic stem cells
Analysis of the transcriptome of ß-catenin flox/- mES cells in comparison with ß-catenin null mES cells or ß-catenin null mES cells stably transfected with an E-cadherin-?-catenin fusion protein. Expression assay was performed using the Affymetrix GeneChip Mouse Gene 1.0 ST array. The experiment inc...
ORGANISM(S): Mus musculus 
2013-05-03 | E-GEOD-44543 | biostudies-arrayexpress
ProteomicsIn-depth protein profiling of mouse hippocampal postsynaptic density using data-independent acquisition proteomics
In the present study, we catalogued the proteome of postsynaptic density (PSD) derived from the hippocampus of three-week old (P19) mice. samples in 100 min gradient time.
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2019-08-27 | MSV000084240 | MassIVE
Transcriptomics3' mRNA-seq of human Ma-Mel-47 (melanoma) and Panc89 (PDAC) cells treated with the USP7 degraders NK266 and NK250, respectively, for 72 h.
3' mRNA-seq was used to study the effects of USP7 degradation by the degraders NK266 and NK250 on gene expression in a human melanoma and PDAC cell line, respectively.
ORGANISM(S): Homo sapiens 
2026-03-27 | E-MTAB-16302 | biostudies-arrayexpress
TranscriptomicsMechanisms and rescue strategies of Calcineurin inhibitor mediated tolerance abrogation
To ensure safety tolerance induction protocols are accompanied by conventional immunosuppressive drugs IS. But IS such as calcineurin inhibitors CNI can interfere with tolerance induction. We investigated the effect of an additional CNI treatment on anti-CD4 mAb-induced tolerance induction upon rat ...
ORGANISM(S): Rattus norvegicus 
2013-09-01 | E-GEOD-40454 | biostudies-arrayexpress
UnknownMissense variants in TAF1 and developmental phenotypes: challenges of determining pathogenicity.
Not available
S-EPMC7187541 | biostudies-literature
UnknownSARS-CoV-2 vaccination modelling for safe surgery to save lives: data from an international prospective cohort study.
Not available
S-EPMC7995808 | biostudies-literature
UnknownTiming of surgery following SARS-CoV-2 infection: an international prospective cohort study.
Not available
S-EPMC8206995 | biostudies-literature
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