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TranscriptomicsSpatio-temporal transcriptome of the human brain
The development of the human brain is a complex and precisely regulated process that unfolds over a protracted period of time. Human-specific features of this process, especially the ways in which highly complex neural circuits of the cerebral cortex form, are likely to be important factors in the e...
ORGANISM(S): Homo sapiens 
2011-10-26 | E-GEOD-25219 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human glioma tumor samples
mRNA expression data were collected from patients with brain tumor to improve diagnostic of gliomas on molecular level.
ORGANISM(S): Homo sapiens 
2007-06-24 | E-GEOD-4290 | biostudies-arrayexpress
GenomicsSpatiotemporal Transcriptome of the Human Brain

Comprehensive knowledge about the spatiotemporal dynamics of the brain transcriptome is essential for a better understanding of neurodevelopment, sexual dimorphism, and evolution, as well as our increased susceptibility to certain brain disorders. We generated and analyzed genome-wide exo...

phs000406.v1.p1 | EGA
TranscriptomicsRecurrent somatic mutations in POLR2A define a distinct subset of meningiomas [RNA-seq]
RNA polymerase II mediates the transcription of all protein-coding genes in eukaryotic cells, a process that is fundamental to life. Genomic mutations in this enzyme have not been previously linked to any pathology in humans, a testament to its indispensable role in cell biology. Based on a combinat...
ORGANISM(S): Homo sapiens 
2016-08-21 | E-GEOD-85133 | biostudies-arrayexpress
GenomicsIntegrated genomic characterization of IDH1 mutant Glioma malignant progression
Gliomas represent approximately 30% of all central nervous system tumors, and 80% of malignant brain tumors. To understand the molecular mechanisms underlying the malignant progression of low-grade Isocitrate Dehydrogenase 1 (IDH1) mutant gliomas, we studied paired tumor samples from 41 patients, co...
EGAS00001001588 | EGA
Genomicsena-DATASET-Yale-19-01-2016-18:21:27:507-133 - samples
Exome sequencing VCF files describing mutations during glioma progression.
EGAD00001001887 | EGA
GenomicsDNA_methylation
DNA methylation microarray
EGAD00010000870 | EGA
GenomicsRna_expression
RNA expression microarray
EGAD00010000869 | EGA
GenomicsYale
Data Access Committee EGAC00001000406
EGAC00001000406 | EGA
TranscriptomicsRecurrent somatic mutations in POLR2A define a distinct subset of meningiomas [array]
RNA polymerase II mediates the transcription of all protein-coding genes in eukaryotic cells, a process that is fundamental to life. Genomic mutations in this enzyme have not been previously linked to any pathology in humans, a testament to its indispensable role in cell biology. Based on a combinat...
ORGANISM(S): Homo sapiens 
2016-08-21 | E-GEOD-84263 | biostudies-arrayexpress
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