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TranscriptomicsTranscription profiling of human polymorphonuclear leukocytes (PMNs) from healthy individuals vs patients with X-linked chronic granulomatous disease
Polymorphonuclear leukocytes (PMNs) were obtained from healthy individuals (Healthy1, Healthy2, Healthy3, and Healthy4) or patients with X-linked chronic granulomatous disease (XCGD1, XCGD2, XCGD3, XCGD4, XCGD5, and XCGD6). The studies were performed in accordance with a protocol approved by the Ins...
ORGANISM(S): Homo sapiens 
2007-09-29 | E-GEOD-935 | biostudies-arrayexpress
UnknownDifferential regulation of staphylococcal virulence by the sensor kinase SaeS in response to neutrophil-derived stimuli.
Not available
S-EPMC4024872 | biostudies-literature
TranscriptomicsPrevention of bone marrow cell apoptosis and regulation of hematopoiesis by type I IFNs during systemic responses to pneumocystis (PC) lung infection
IFrag-/- but not RAG-/- mice develop rapidly progressing bone marrow failure in response to PC lung infection. Changes contributing to accelerated bone marrow cell apoptosis in IFrag-/- mice appear to be initiated around day 7 post infection. To gain further insight into the mechanism underlying the...
ORGANISM(S): Mus musculus 
2012-02-20 | E-GEOD-27835 | biostudies-arrayexpress
UnknownStaphylococcus aureus SaeR/S-regulated factors reduce human neutrophil reactive oxygen species production.
Not available
S-EPMC5069094 | biostudies-literature
UnknownThe SaeR/S gene regulatory system is essential for innate immune evasion by Staphylococcus aureus.
Not available
S-EPMC2799113 | biostudies-literature
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