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ProteomicsiTRAQ-based quantitative proteomic analysis of nuclear proteome in VPS35-depleted HeLa cells
Stable VPS35 knockdown HeLa cells were generated using lentiviral short hairpin RNA (shRNA) construct. Isobaric tags for relative and absolute quantitation (iTRAQ)-based mass spectrometry was used to measure the changes of nuclear protein abundance in VPS35-depleted HeLa cells.
ORGANISM(S): Homo sapiens (Human) 
2022-08-12 | PXD027166 | Pride
Itraq  vps35  nuclear proteome  hela cells 
TranscriptomicsParkinson's disease genes VPS35 and EIF4G1 interact genetically and converge on alpha-synuclein
Parkinson's disease (PD) is a common human neurodegenerative movement disorder. Studies of the genetic forms of PD have helped to reveal disease mechanisms. Functional interactions between some Parkinson's disease (PD) genes, like PINK1 and parkin, have been identified, but whether other ones intera...
ORGANISM(S): Saccharomyces cerevisiae 
2014-12-19 | E-GEOD-64304 | biostudies-arrayexpress
GenomicsEffect of VPS35 on gene expression in MKN28 gastric cancer cells
Effect of VPS35 on gene expression in MKN28 gastric cancer cells
PRJNA865265 | ENA
GenomicsRNA Seq of wild-type and VPS35-D620N-expressing SH-SY5Y cells
RNA Seq of wild-type and VPS35-D620N-expressing SH-SY5Y cells
PRJNA480517 | ENA
TranscriptomicsEffect of VPS35 on gene expression in MKN28 gastric cancer cells
To investigate the function of VPS35 in the regulation of gastric cancer cell proliferation, we established MKN28 cell lines in which VPS35 has been knocked down by shRNA.
ORGANISM(S): Homo sapiens 
2023-05-31 | GSE210320 | GEO
ProteomicsNCOMMS-23-38170-T Mutant mice with rod-specific VPS35 deletion exhibit visual deficit, synaptopathy, and retinal synucleinopathy” by Fu, Table 1
Study of VPS35 interacting proteins in mouse retinas.
ORGANISM(S): Mus musculus (Mouse) 
2024-06-27 | PXD044890 | Pride
Retina Mouse Vps35 
GenomicsParkinson's disease genes VPS35 and EIF4G1 interact genetically and converge on alpha-synuclein
Parkinson's disease (PD) is a common human neurodegenerative movement disorder. Studies of the genetic forms of PD have helped to reveal disease mechanisms. Functional interactions between some Parkinson's disease (PD) genes, like PINK1 and parkin, have been identified, but whether other ones intera...
ORGANISM(S): Saccharomyces cerevisiae 
2014-12-19 | GSE64304 | GEO
UnknownVPS35, the Retromer Complex and Parkinson's Disease.
Not available
S-EPMC5438477 | biostudies-literature
UnknownVPS35 mutations in Parkinson disease.
Not available
S-EPMC3135796 | biostudies-literature
TranscriptomicsRNA Seq of wild-type and VPS35-D620N-expressing SH-SY5Y cells
SH-SY5Y were created to stably express wild-type or VPS35-D620N (CMV-promoter driven) using a lentiviral vector (Vira power). Non-transduced cells were eliminated with blasticidin resistance gene included in viral cassette
ORGANISM(S): Homo sapiens 
2018-07-11 | GSE116900 | GEO
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