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ProteomicsMitochondrial L-2-hydroxyglutarate is a physiologic signaling metabolite
L-2-hydroxyglutarate (L-2-HG) is a low-abundance metabolite in mammals, due to the mitochondrial enzyme L-2-HG dehydrogenase (L2HGDH), which oxidizes L-2-HG to 2-oxoglutarate (2-OG) to prevent its accumulation. In humans lacking L2HGDH activity, L-2-HG builds up, leading to L-2-HG aciduria, a rare c...
ORGANISM(S): Mus musculus (Mouse) 
2026-03-31 | PXD054020 | Pride
Mitochondria Metabolism 2-og-dependent dioxygenases Metabolite signaling Gene expression regulation 
UnknownSuper-resolution optical DNA Mapping via DNA methyltransferase-directed click chemistry.
Not available
S-EPMC3985630 | biostudies-literature
UnknownChemoenzymatic synthesis and utilization of a SAM analog with an isomorphic nucleobase.
Not available
S-EPMC4927405 | biostudies-literature
UnknownMethyltransferase-Directed Labeling of Biomolecules and its Applications.
Not available
S-EPMC5502580 | biostudies-literature
UnknownEfficacy of Veno-Arterial Extracorporeal Life Support in Adult Patients with Refractory Cardiogenic Shock.
Not available
S-EPMC9309772 | biostudies-literature
UnknownCitizen scientists: Unveiling motivations and characteristics influencing initial and sustained participation in an agricultural project.
Not available
S-EPMC11104611 | biostudies-literature
TranscriptomicsGene expression study of macrophages during early foreign body reaction
Foreign body reaction (FBR), initiated by adherence of macrophages to biomaterials, is associated with several complications. Searching for mechanisms potentially useful to overcome these complications, we have established the signaling role of macrophages in the development of FBR. This study profi...
ORGANISM(S): Rattus norvegicus 
2013-01-23 | E-GEOD-21682 | biostudies-arrayexpress
UnknownAssessing the relation between protein phosphorylation, AlphaFold3 models, and conformational variability.
Not available
S-EPMC12723721 | biostudies-literature
ProteomicsProteomics analysis of tibialis anterior muscle and descending thoracic aorta from Mustn1 whole-body knockout mice and wild-type littermates
Skeletal muscle is a highly adaptive tissue that changes with many physiological stimuli and is composed of many cell types. Upon muscle injury, the concerted action of these cells is required to proceed through the process of inflammation, extracellular matrix remodeling, and restoration of functio...
ORGANISM(S): Mus musculus (Mouse) 
2024-05-24 | PXD046610 | Pride
Proteomics Aorta Skeletal muscle Mustn1 
UnknownA new ergasilid copepod from lates perches in East Africa: morphology, phylogenetics, and genetic structure of <i>Ergasilus ereimia</i> sp. nov.
Not available
S-EPMC12908592 | biostudies-literature
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