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TranscriptomicsFiorentino 2006-7 dermatomyositis, lupus, control skin
Background: Dermatomyositis (DM) is an autoimmune disease that mainly affects the skin, muscle, and lung. The pathogenesis of skin inflammation in DM is not well understood. Methodology and Findings: We analyzed genome-wide expression data in DM skin and compared them to those from healthy controls....
ORGANISM(S): Homo sapiens 
2012-01-12 | E-GEOD-32245 | biostudies-arrayexpress
TranscriptomicsTranscriptome Alteration in the Diabetic Heart by Rosiglitazone: Implications for Cardiovascular Mortality
The type 2 diabetes medication, rosiglitazone, has come under scrutiny for possibly increasing the risk of cardiac disease and death. To investigate the effects of rosiglitazone on the diabetic heart, we performed cardiac transcriptional profiling of a murine model of type 2 diabetes, the C57BL/KLS...
ORGANISM(S): Mus musculus 
2012-03-28 | E-GEOD-36875 | biostudies-arrayexpress
ProteomicsComprehensive respiratory phenomics across multiple models of mitochondrial protein hyperacylation reveals a paradoxically marginal impact on bioenergetics
Acyl CoA metabolites derived from catabolism of carbon fuels can react with lysine residues of mitochondrial proteins, giving rise to a large family of post-translation modifications (PTMs). Mass spectrometry-based detection of thousands of acyl-PTMs scattered throughout the proteome has established...
ORGANISM(S): Mus Musculus (mouse) 
2019-02-07 | PXD011375 | JPOST Repository
TranscriptomicsGenes regulated in mouse liver by expressing ectopically hURI in hepatocytes
RNA-seq was performed using the RNA extracted from the bottom half of right lobe of mouse livers. Mice fall into two groups, mutant group which express ectopic hURI and their control littermates which do not express hURI. Two time points were considered in the study, 1-week-old mice, expressing hURI...
ORGANISM(S): Mus musculus 
2014-12-11 | E-GEOD-48654 | biostudies-arrayexpress
UnknownTherapies to Restore Consciousness in Patients with Severe Brain Injuries: A Gap Analysis and Future Directions.
Not available
S-EPMC8266715 | biostudies-literature
UnknownThe Curing Coma Campaign: Framing Initial Scientific Challenges-Proceedings of the First Curing Coma Campaign Scientific Advisory Council Meeting.
Not available
S-EPMC7392933 | biostudies-literature
UnknownImpact of Parental or First-Degree Family History of Diabetes on Diabetes Incidence and Progression During Long-term Follow-up in the Diabetes Prevention Program Outcomes Study.
Not available
S-EPMC12451838 | biostudies-literature
UnknownAssociation of BMI and Cognitive Performance in the Diabetes Prevention Program Outcomes Study.
Not available
S-EPMC12636062 | biostudies-literature
UnknownMapping the genetic landscape across 14 psychiatric disorders.
Not available
S-EPMC12779569 | biostudies-literature
UnknownSociodemographic, Clinical, and Psychosocial Predictors of Short- and Long-term Study Retention in the Diabetes Prevention Program (DPP) Outcomes Study (DPPOS).
Not available
S-EPMC12451849 | biostudies-literature
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