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Although several markers have been associated with the characterization of regulatory T cells (Treg) and their function, no studies have investigated the dynamics of their phenotype during infection. Since the necessity of Treg to control immunopathology has been demonstrated, we used the chronic he...
ORGANISM(S): Mus musculus 
HB digestion with Pepsin and Napsin t=20, 60 and 120 min Analysis by nanoLC-ESI-iTRAP-OrbiTrap
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2021-05-10 | MSV000087400 | MassIVE
In this work, we generated an extensive dataset describing the metabolome and lipidome of 39 SARS-CoV-2 infected patients versus age- and gender-matched 39 healthy controls. We implemented state of the art acquisition techniques including IDA and SWATH-DIA to ensure a holistic insight in the lipidom...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
The EPIGEN-Brasil Initiative is so far the largest Latin American initiative in population genomics and genetic epidemiology. Its main goal is to study the association between genetic variants found in the Brazilian population and complex diseases, taking into account one of the most important chara...
Data Access Committee EGAC00001000330
Epigen-Brasil samples using HumanOmni2.5
To explore how bacterial lipoproteins (i.e. TLR2 ligands) increased macrophage ploidy via mitotic defects, we performed global analysis of cell cycle gene expression changes induced by bacterial lipoproteins. FSL-1 (Pam2CGDPKHPKSF) is a synthetic lipoprotein that represents the N-terminal part of th...
ORGANISM(S): Mus musculus 
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