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TranscriptomicsTranscription profiling of human mesenchymal stem cells to determine changes over the course of cellular aging
To determine gene expression changes during in vitro senescence of MSC we have analyzed differential expression of the corresponding early passage (P2) and senescent passage (PX). There were global changes in the gene expression profile that were reproducible in three independent donor samples. Expe...
ORGANISM(S): Homo sapiens 
2008-10-20 | E-GEOD-9593 | biostudies-arrayexpress
UnknownRandomized phase III trial of ABVD versus Stanford V with or without radiation therapy in locally extensive and advanced-stage Hodgkin lymphoma: an intergroup study coordinated by the Eastern Cooperative Oncology Group (E2496).
Not available
S-EPMC3574266 | biostudies-literature
UnknownRandomized Phase III Trial Comparing ABVD Plus Radiotherapy With the Stanford V Regimen in Patients With Stages I or II Locally Extensive, Bulky Mediastinal Hodgkin Lymphoma: A Subset Analysis of the North American Intergroup E2496 Trial.
Not available
S-EPMC4451176 | biostudies-literature
TranscriptomicsTranscription profiling of human mesenchymal stromal cells to reveal senescence associated gene expression changes
Transcription profiling of human mesenchymal cells (MSCs) after ex vivo expansion under culture conditions supporting extensive cell proliferation. Highly efficient cell expansion within short time (~40 days) and comparison of gene expression profiles from MSCs after primary seeding, defined as earl...
ORGANISM(S): Homo sapiens 
2009-12-31 | E-MEXP-1997 | biostudies-arrayexpress
ProteomicsStructural basis of human transcription-DNA repair coupling
Transcription-coupled DNA repair (TCR) efficiently removes bulky DNA lesions from transcribed parts of the genome and constitutes a major defence against DNA damage by UV irradiation. TCR begins when RNA polymerase II (Pol II) stalls at a DNA lesion and recruits the Cockayne syndrome protein CsB, th...
ORGANISM(S): Homo sapiens (Human) Sus scrofa domesticus (domestic pig) 
2022-02-17 | PXD025328 | Pride
Protein-protein crosslinking Transcription-dna repair Ubiquitination analysis 
UnknownTRIM14 Is a Key Regulator of the Type I IFN Response during Mycobacterium tuberculosis Infection.
Not available
S-EPMC7313415 | biostudies-literature
ProteomicsProtein abundance of AKT and ERK pathway components governs cell-type-specific regulation of proliferation
Signaling through the AKT and ERK pathways controls cell proliferation. However, the integrated regulation of this multistep process, involving signal processing, cell growth and cell-cycle progression, is poorly understood. Here we study different murine hematopoietic cell types, in which AKT and E...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-03-31 | MSV000080844 | MassIVE
TranscriptomicsDifferential expression of Dictyostelium discoideum AX2 upon infection with wt L. pneumophila JR32 vs. uninfected 1h p.i. (timecourse experiment)
Differential gene expression of Dictyostelium discoideum after infection with Legionella pneumophila in comparison to uninfected cells was investigated using DNA microarrays. Investigation of a 48 h time course of infection revealed several clusters of co-regulated genes, an enrichment of preferenti...
ORGANISM(S): Dictyostelium discoideum 
2013-09-25 | E-GEOD-50963 | biostudies-arrayexpress
TranscriptomicsDifferential expression of Dictyostelium discoideum AX2 upon infection with wt L. pneumophila JR32 vs. uninfected 24h p.i. (timecourse experiment)
Differential gene expression of Dictyostelium discoideum after infection with Legionella pneumophila in comparison to uninfected cells was investigated using DNA microarrays. Investigation of a 48 h time course of infection revealed several clusters of co-regulated genes, an enrichment of preferenti...
ORGANISM(S): Dictyostelium discoideum 
2013-09-25 | E-GEOD-50964 | biostudies-arrayexpress
TranscriptomicsDifferential expression of Dictyostelium discoideum AX2 upon infection with wt L. pneumophila JR32 vs. uninfected 48h p.i. (timecourse experiment)
Differential gene expression of Dictyostelium discoideum after infection with Legionella pneumophila in comparison to uninfected cells was investigated using DNA microarrays. Investigation of a 48 h time course of infection revealed several clusters of co-regulated genes, an enrichment of preferenti...
ORGANISM(S): Dictyostelium discoideum 
2013-09-25 | E-GEOD-50965 | biostudies-arrayexpress
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