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TranscriptomicsMaintenance of DNA methylation in embryonic stem cells depends on the histone H3K9 methyltransferases
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Mus musculus 
2014-06-03 | E-GEOD-47894 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of pancreas from Wistar or WBN/Kob rats to study chronic pancreatitis
Wistar rats, purchased from BRL (Fullinsdorf/BL, Switzerland), and WBN/Kob rats, purchased from SLC Inc. (Shizuoka, Japan), were specific pathogen-free. Rats were housed in groups of maximally 4 instandard cages (1,820 cm2 bottom area) and kept in our animal facility for various time periods between...
ORGANISM(S): Rattus norvegicus 
2009-05-15 | E-MEXP-1704 | biostudies-arrayexpress
TranscriptomicsExpression profiling of Ovine Herpesvirus 2-infected lymph nodes from Bos taurus
We hypothesized that the gene expression pattern of OvHV-2 may be important to understand the pathogenesis of malignant catarrhal fever (MCF). Therefore, RNA was extracted from lymph nodes of animals with MCF and healthy controls to be analyzed by a custom-made microarray. Two regions on the viral g...
ORGANISM(S): Bos taurus 
2010-05-15 | E-GEOD-13853 | biostudies-arrayexpress
GenomicsMaintenance of DNA methylation in embryonic stem cells depends on the histone H3K9 methyltransferases (Dnmt3ab KO ChIP-Seq)
During mammalian development DNA methylation patterns need to be reset in primordial germ cells (PGC) and preimplantation embryos. However, many retro-transposons and imprinted genes are resistant to such global epigenetic reprogramming via hitherto undefined mechanisms. Here, we report that some of...
ORGANISM(S): Mus musculus 
2014-06-03 | E-GEOD-47878 | biostudies-arrayexpress
TranscriptomicsMaintenance of DNA methylation in embryonic stem cells depends on the histone H3K9 methyltransferases (Dnmt3ab KO RNA-Seq)
During mammalian development DNA methylation patterns need to be reset in primordial germ cells (PGC) and preimplantation embryos. However, many retro-transposons and imprinted genes are resistant to such global epigenetic reprogramming via hitherto undefined mechanisms. Here, we report that some of...
ORGANISM(S): Mus musculus 
2014-06-03 | E-GEOD-47883 | biostudies-arrayexpress
GenomicsMaintenance of DNA methylation in embryonic stem cells depends on the histone H3K9 methyltransferases (K9 KO ChIP-Seq)
During mammalian development DNA methylation patterns need to be reset in primordial germ cells (PGC) and preimplantation embryos. However, many retro-transposons and imprinted genes are resistant to such global epigenetic reprogramming via hitherto undefined mechanisms. Here, we report that some of...
ORGANISM(S): Mus musculus 
2014-06-03 | E-GEOD-47887 | biostudies-arrayexpress
GenomicsMaintenance of DNA methylation in embryonic stem cells depends on the histone H3K9 methyltransferases (Dnmt3ab KO Methyl-Seq)
During mammalian development DNA methylation patterns need to be reset in primordial germ cells (PGC) and preimplantation embryos. However, many retro-transposons and imprinted genes are resistant to such global epigenetic reprogramming via hitherto undefined mechanisms. Here, we report that some of...
ORGANISM(S): Mus musculus 
2014-06-03 | E-GEOD-47893 | biostudies-arrayexpress
GenomicsMaintenance of DNA methylation in embryonic stem cells depends on the histone H3K9 methyltransferases (K9 KO 5hmC-capture-seq)
During mammalian development DNA methylation patterns need to be reset in primordial germ cells (PGC) and preimplantation embryos. However, many retro-transposons and imprinted genes are resistant to such global epigenetic reprogramming via hitherto undefined mechanisms. Here, we report that some of...
ORGANISM(S): Mus musculus 
2014-06-03 | E-GEOD-47892 | biostudies-arrayexpress
GenomicsMaintenance of DNA methylation in embryonic stem cells depends on the histone H3K9 methyltransferases (K9 KO Methyl-Seq)
During mammalian development DNA methylation patterns need to be reset in primordial germ cells (PGC) and preimplantation embryos. However, many retro-transposons and imprinted genes are resistant to such global epigenetic reprogramming via hitherto undefined mechanisms. Here, we report that some of...
ORGANISM(S): Mus musculus 
2014-06-03 | E-GEOD-47890 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human TLR2/1 stimulated human monocytes with the Mycobacterium tuberculosis derived 19kDa lipopeptide reveals Toll-like receptor triggering of a vitamin D-mediated human antimicrobial response
In innate immune responses, activation of Toll-like receptors (TLRs) triggers direct antimicrobial activity against intracellular bacteria, which in murine, but not human, monocytes and macrophages is mediated principally by nitric oxide. We report here that TLR activation of human macrophages up-re...
ORGANISM(S): Homo sapiens 
2008-06-17 | E-GEOD-8921 | biostudies-arrayexpress
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