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ProteomicsPairwise screening of viral-bacterial co-infections in vitro reveals molecular interaction points that affect pathogen proliferation and host cell viability
The broadening of accessible methodologies has enabled mechanistic insights into single-pathogen infections, yet the molecular mechanisms underlying co-infections remain largely elusive, despite their clinical frequency and relevance, generally exacerbating symptom severity and fatality.Here, we des...
ORGANISM(S): Mus musculus (Mouse) 
2024-07-25 | PXD050625 | Pride
Innate immune response Co-infection Screening Host-pathogen interaction 
TranscriptomicsBezafibrate improves insulin sensitivity and metabolic flexibility in STZ-treated diabetic mice
Bezafibrate (BEZ), a pan activator of peroxisome proliferator-activated receptors (PPARs), is generally used to treat hyperlipidemia. Clinical trials on patients suffering from type 2 diabetes indicated that BEZ also has beneficial effects on glucose metabolism, but the underlying mechanisms remain ...
ORGANISM(S): Mus musculus 
2016-06-29 | E-GEOD-79008 | biostudies-arrayexpress
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