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MetabolomicsMulti-omics analysis of host airway responses in pediatric Mycoplasma pneumoniae pneumonia reveals potential mechanisms of disease exacerbation caused by co-infection

Respiratory viral co-infections in children with Mycoplasma pneumoniae pneumonia (MPP) are common and cause severe clinical manifestations. However, the exact pathogenic mechanisms of MPP co-infections are still unclear. In this study, we conducted a large-scale clinical analysis of 3,106 MPP pat...

2025-11-25 | MTBLS12635 | MetaboLights
MetabolomicsElevated CO2 and virus infection impacts wheat and aphid metabolism

INTRODUCTION: The aphid Rhopalosiphum padi L. is a vector of Barley yellow dwarf virus (BYDV) in wheat and other economically important cereal crops. Increased atmospheric CO2 has been shown to alter plant growth and metabolism, enhancing BYDV disease in wheat. However, the bioch...

2019-01-16 | MTBLS622 | MetaboLights
ModelsMukandavire2009 - Model for HIV-Malaria co-infection
Mathematical model for HIV, malaria and HIV-malaria co-infection.
2018-05-23 | MODEL1805230001 | BioModels
GenomicsCo-Infection Samples
Co-Infection Samples Metagenome
PRJNA196307 | ENA
ProteomicsResponse of Galleria to co-infection by Candida and Staphylococcus.
Polymicrobial infections are intrinsically less susceptible to antimicrobial therapy, are more invasive and can induce enhanced inflammatory responses leading to negative clinical outcomes. The importance of studying the interaction between microbes themselves and their interactions with their host ...
ORGANISM(S): Galleria mellonella 
2020-02-24 | PXD014273 | Pride
Infection Galleria Immunity Staphylococcus Co-infection. anti-microbial Candida Mini-model 
ProteomicsHIV/HCV co-infection proteomics
Hepatic complications of HCV infection, including fibrosis and cirrhosis are accelerated in HIV-infected individuals. Although liver biopsy remains the gold standard for staging HCV-associated liver disease, this test can result in serious complications and is subject to sampling error. These challe...
ORGANISM(S): Homo sapiens (Human) 
2018-04-09 | PXD009007 | Pride
Seldi Proteomics Hcv Co-infection Liver Fibrosis Hiv Maldi Biomarker discovery Human 
GenomicsCo-infection of fungi and bacteria in brain tissue of Alzheimer’s patients.
Metagenomics analysis reveals co-infection of fungi and bacteria isolated from different regions of brain tissue from elderly persons and patients with Alzheimer's disease.
EGAS00001002766 | EGA
ProteomicsStreptococcus pneumoniae and IAV co infection induces altered polyubiquitination in A549 cells
Epithelial cells are the first line of defense within the lung. Disruption of the epithelial barrier by pathogens enables the systematic dissemination of bacteria or viruses within the host, leading to severe diseases with fatal outcomes. Thus, the lung epithelium can be damaged by seasonal and pand...
ORGANISM(S): Homo sapiens (Human) 
2022-02-24 | PXD028465 | Pride
Co infection A549 Ubiquitin Influenza a virus Streptococcus pneumoniae d39 
TranscriptomicsUnveiling immune interference: How dendritic cell response to co-infection with Aspergillus fumigatus is modulated by human cytomegalovirus and its virokine CMVIL10
We confronted moDCs with wildtype (WT) HCMV TB40E BAC4 or ΔUL111A (HCMV lacking CMVIL-10) with an MOI of 3 and/or A. fumigatus germ tubes with an MOI of 0.5 for 9 h, either individually (single infection) or simultaneously (co-infection), and performed RNA-seq. moDCs were incubated with or without 5...
ORGANISM(S): Homo sapiens 
2025-09-09 | E-MTAB-15110 | biostudies-arrayexpress
GenomicsProtozoan Co-infection Is Associated with Gut Microbiome Composition among School Children in Hawassa, southern Ethiopia
Protozoan Co-infection-Gut Microbiome
PRJEB127347 | ENA
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