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ProteomicsA transient protein folding response targets aggregation in the early phase of TDP-43-mediated disease
Understanding the mechanisms that drive TDP-43 pathology is integral to combating amyotrophic lateral sclerosis (ALS) and frontotemporal lobar degeneration (FTLD). Here we generated a longitudinal quantitative proteomic map of the cortex from the cytoplasmic TDP-43 rNLS8 mouse model of ALS and FTLD ...
ORGANISM(S): Mus musculus (Mouse) 
2024-01-31 | PXD042382 | Pride
Ftld Longitudinal Als Cortex Mouse Proteinopathy Motor neuron disease Mnd Tdp-43 Lc-ms/ms Tandem mass tagging Amyotrophic lateral sclerosis Frontotemporal dementia Ftd Frontotemporal lobar degeneration 
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