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MetabolomicsDysregulation of Streptococcus pneumoniae zinc homeostasis breaks ampicillin resistance in a pneumonia infection model

Streptococcus pneumoniae is the primary cause of community-acquired bacterial pneumonia with rates of penicillin and multi-drug resistance exceeding 80% and 40%, respectively. The innate immune response generates a variety of antimicrobial agents to control infection including zinc stres...

2022-02-23 | MTBLS318 | MetaboLights
UnknownRecall of preexisting cross-reactive B cell memory after Omicron BA.1 breakthrough infection.
Not available
S-EPMC9097882 | biostudies-literature
TranscriptomicsThe transcriptomic basis of oviposition behaviour in the parasitoid wasp Nasonia vitripennis
For many behaviours studied at the phenotypic level, we have little or no idea of where to start searching for “candidate” genes: the transcriptome provides such a starting point. Here we consider transcriptomic changes associated with oviposition in the parasitoid wasp Nasonia vitripennis. Oviposit...
ORGANISM(S): Nasonia vitripennis 
2013-07-22 | E-GEOD-43352 | biostudies-arrayexpress
UnknownEvolution of antibody immunity following Omicron BA.1 breakthrough infection.
Not available
S-EPMC9516849 | biostudies-literature
TranscriptomicsAberrant global methylation patterns affect the molecular pathogenesis and prognosis of human multiple myeloma
We have used genome-wide methylation microarrays to analyze differences in CpG methylation patterns in cells relevant to the pathogenesis of myeloma plasma cells, including B cells, normal plasma cells, MGUS, presentation myeloma, and plasma cell leukemia (PCL). We show that methylation patterns in ...
ORGANISM(S): Homo sapiens 
2010-10-18 | E-GEOD-21304 | biostudies-arrayexpress
TranscriptomicsA compendium of myeloma associated chromosomal copy number abnormalities and their prognostic value
To obtain a comprehensive genomic profile of presenting multiple myeloma cases we performed high resolution single nucleotide polymorphism (SNP) mapping array analysis in 114 samples alongside 258 samples analysed by U133 Plus 2.0 expression array (Affymetrix). We examined DNA copy number alteratio...
ORGANISM(S): Homo sapiens 
2010-11-02 | E-GEOD-21349 | biostudies-arrayexpress
UnknownRisk of covid-19 related deaths for SARS-CoV-2 omicron (B.1.1.529) compared with delta (B.1.617.2): retrospective cohort study.
Not available
S-EPMC9344192 | biostudies-literature
UnknownNeutralising antibody potency against SARS-CoV-2 wild-type and omicron BA.1 and BA.4/5 variants in patients with inflammatory bowel disease treated with infliximab and vedolizumab after three doses of COVID-19 vaccine (CLARITY IBD): an analysis of a prospective multicentre cohort study.
Not available
S-EPMC9757903 | biostudies-literature
TranscriptomicsDNA methylation profiles of human blood samples from a severe developmental disorder and controls
Human DNA methylation Beadchip v1.2 was used to obtain n=113 Illumina DNA methylation array from whole blood samples. The main goal of the study was to measure the epigenetic age (also known as DNA methylation age) of subjects with a severe developmental disorder (known as syndrome X) and controls. ...
ORGANISM(S): Homo sapiens 
2015-05-28 | E-GEOD-64495 | biostudies-arrayexpress
UnknownAccommodation of two diatomic molecules in cytochrome bo: insights into NO reductase activity in terminal oxidases.
Not available
S-EPMC2651033 | biostudies-literature
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