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ProteomicsSmoothened Transduces Hedgehog Signals via Activity-Dependent Sequestration of PKA Catalytic Subunits
The Hedgehog (Hh) pathway is essential for organ development, homeostasis, and regeneration. Dysfunction of this cascade drives several cancers. To control expression of pathway target genes, the G protein-coupled receptor (GPCR) Smoothened (SMO) activates glioma-associated (GLI) transcription facto...
ORGANISM(S): Homo Sapiens 
2021-04-25 | PXD023893 | panorama
UnknownSystemic therapy in men with metastatic castration-resistant prostate cancer:American Society of Clinical Oncology and Cancer Care Ontario clinical practice guideline.
Not available
S-EPMC4876355 | biostudies-literature
TranscriptomicsTranscription profiling of Rhizobium leguminosarum biovar viciae strain 3841grown on AMS minimal medium with either succinate ammonia or glucose ammonia as carbon and nitrogen sources
Rhizobium leguminosarum bivar viciae strain 3841 was grown on AMS minimal medium with either succinate ammonia or glucose ammonia as carbon and nitrogen sources. Gene expression was compared between the two crabon sources. Total RNA was amplified using Genispheres SenseAmp kit.
ORGANISM(S): Rhizobium leguminosarum 
2008-12-18 | E-MEXP-1962 | biostudies-arrayexpress
UnknownClinical diversity and treatment results in Tegumentary Leishmaniasis: A European clinical report in 459 patients.
Not available
S-EPMC8544871 | biostudies-literature
TranscriptomicsA compendium of myeloma associated chromosomal copy number abnormalities and their prognostic value
To obtain a comprehensive genomic profile of presenting multiple myeloma cases we performed high resolution single nucleotide polymorphism (SNP) mapping array analysis in 114 samples alongside 258 samples analysed by U133 Plus 2.0 expression array (Affymetrix). We examined DNA copy number alteratio...
ORGANISM(S): Homo sapiens 
2010-11-02 | E-GEOD-21349 | biostudies-arrayexpress
UnknownAn actin-WHAMM interaction linking SETD2 and autophagy.
Not available
S-EPMC8021614 | biostudies-literature
UnknownEpigenetic response to hyperoxia in the neonatal lung is sexually dimorphic.
Not available
S-EPMC7509469 | biostudies-literature
GenomicDobyns DBD

Study 1
2R01-NS050375 (PI: DOBYNS, William B.)
The genetic basis of mid-hindbrain malformations
Our general goal for this project is to advance our understanding of human developmental disorders that involve the brainstem and cerebellum - brain structures derived from the embryoni...

phs000455 | dbGaP
TranscriptomicsGNF mouse atlas_macrophages
Monocytes and macrophages express an extensive repertoire of G Protein-Coupled Receptors (GPCRs) that regulate inflammation and immunity. In this study we performed a systematic microarray analysis of GPCR expression in primary mouse tissues to identify family members that are either enriched in mac...
ORGANISM(S): Mus musculus 
2008-05-05 | E-GEOD-11339 | biostudies-arrayexpress
TranscriptomicsTranscription profiling time series of Rhizobium leguminosarum from pea nodules compared to cells grown in free-living culture on succinate ammonia AMS
Time course of bacteroid formation. Bacteroids were harvested from pea nodules at 7, 15 and 21 d after inoculation onto 7 d old pea plants. The transcription profile of each bacteroid sample at the 3 time points was compared to cells grown in free-living culture on succinate ammonia AMS.
ORGANISM(S): Rhizobium leguminosarum 
2008-11-27 | E-MEXP-1918 | biostudies-arrayexpress
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