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TranscriptomicsCXCR4 activation maintains a stem cell population in tamoxifen-resistant breast cancer cells through AHR signaling
Targeting the estrogen signaling pathway has proved to be of great value in the treatment of human breast cancer. Tamoxifen, a selective estrogen receptor modulator (SERM), is the most widely used antiestrogen. However, only 40-50% of patients with estrogen receptor (ER) positive breast cancer benef...
ORGANISM(S): Homo sapiens 
2012-12-21 | E-GEOD-31831 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human samples of multiple myeloma patients with and without bone lytic lesion by MRI
This series represents samples of multiple myeloma patients with and without bone lytic lesion by MRI.
ORGANISM(S): Homo sapiens 
2007-09-25 | E-GEOD-755 | biostudies-arrayexpress
UnknownRacial/Ethnic Differences In COVID-19 Screening, Hospitalization, And Mortality In Southeast Wisconsin.
Not available
S-EPMC7768944 | biostudies-literature
TranscriptomicsGNF mouse atlas_macrophages
Monocytes and macrophages express an extensive repertoire of G Protein-Coupled Receptors (GPCRs) that regulate inflammation and immunity. In this study we performed a systematic microarray analysis of GPCR expression in primary mouse tissues to identify family members that are either enriched in mac...
ORGANISM(S): Mus musculus 
2008-05-05 | E-GEOD-11339 | biostudies-arrayexpress
UnknownCXCR4 activation maintains a stem cell population in tamoxifen-resistant breast cancer cells through AhR signalling.
Not available
S-EPMC3389396 | biostudies-literature
TranscriptomicsTranscription profiling of human cell lines and tissues (GNF/Novartis)
The tissue-specific pattern of mRNA expression can indicate important clues about gene function. High-density oligonucleotide arrays offer the opportunity to examine patterns of gene expression on a genome scale. Toward this end, we have designed custom arrays that interrogate the expression of the ...
ORGANISM(S): Homo sapiens 
2011-11-08 | E-AFMX-5 | biostudies-arrayexpress
TranscriptomicsLarge-scale analysis of the human transcriptome - Novartis dataset
High-throughput gene expression profiling has become an important tool for investigating transcriptional activity in a variety of biological samples. To date, the vast majority of these experiments have focused on specific biological processes and perturbations. Here, we have generated and analyzed ...
ORGANISM(S): Homo sapiens 
2002-12-06 | E-GEOD-96 | biostudies-arrayexpress
UnknownMutational Spectrum, Copy Number Changes, and Outcome: Results of a Sequencing Study of Patients With Newly Diagnosed Myeloma.
Not available
S-EPMC6485456 | biostudies-literature
UnknownA gene atlas of the mouse and human protein-encoding transcriptomes.
Not available
S-EPMC395923 | biostudies-literature
TranscriptomicsInhibitors that block initiation of wall teichoic acid biosynthesis sensitize methicillin-resistant Staphylococcus aureus to beta-lactams
Methicillin resistance in Staphylococcus aureus depends on the production of mecA, which encodes penicillin-binding protein 2A (PBP2A), an acquired peptidoglycan transpeptidase with reduced susceptibility to beta-lactam antibiotics. Here, we show that preventing the expression of wall teichoic acids...
ORGANISM(S): Staphylococcus aureus 
2010-10-19 | E-GEOD-24439 | biostudies-arrayexpress
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