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TranscriptomicsDNA methylation profiles in the uterus during early pregnancy
Co-ordinated regulation of endometrial gene expression is essential for successful pregnancy establishment. A non-receptive uterine environment may be a key contributor to pregnancy loss, as the majority of pregnancy losses occur prior to embryo implantation. DNA methylation has been highlighted as...
ORGANISM(S): Bos taurus 
2013-05-03 | E-GEOD-43501 | biostudies-arrayexpress
TranscriptomicsGene expression of human paediatric osteosarcoma tumour samples relative to normal human osteoblasts
Gain or loss of genes and deregulation of gene expression can result in cumulative and progressive disruptions of normal cellular functions. Cancer-specific changes in gene expression play an essential role in cancer occurrence, and ultimately lead to cancer-related self-sufficiency in growth signal...
ORGANISM(S): Homo sapiens 
2010-04-09 | E-GEOD-12865 | biostudies-arrayexpress
Unknown1088. A Whole-Body Quantitative System Pharmacology Physiologically-Based Pharmacokinetic (QSP/PBPK) Model to Support Dose Selection of ADG20: an Extended Half-Life Monoclonal Antibody Being Developed for the Treatment of Coronavirus Disease (COVID-19)
Not available
S-EPMC8643832 | biostudies-literature
TranscriptomicsDNA methylation profiles in the uterus during subclinical endometritis
Post-partum uterine inflammation (endometritis) is associated with lower fertility at both the time of infection and after the inflammation has resolved. It was hypothesized that aberrant DNA methylation may be involved in the sub-fertility associated with post-partum uterine inflammation. The objec...
ORGANISM(S): Bos taurus 
2015-05-07 | E-GEOD-60831 | biostudies-arrayexpress
TranscriptomicsExpression data from proximal jejunum of WT vs. TLR2 KO mice after methotrexate (MTX) treatment
The role of innate immunity in modulating severity of chemotherapy-induced complications is so far unclear. The aim of this study was to determine how TLR2 may influence MTX-induced mucositis in the small intestine in mice. We used microarrays to assess gene expression profiles in proximal jejunum o...
ORGANISM(S): Mus musculus 
2015-01-24 | E-GEOD-56426 | biostudies-arrayexpress
TranscriptomicsModulation of the immune system during postpartum uterine inflammation
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Bos taurus 
2015-05-07 | E-GEOD-60832 | biostudies-arrayexpress
UnknownTLR signaling modulates side effects of anticancer therapy in the small intestine.
Not available
S-EPMC4338614 | biostudies-literature
Unknown1089. Use of a Whole-Body Quantitative System Pharmacology Physiologically-Based Pharmacokinetic (QSP/PBPK) Model to Support Dose Selection of ADG20: an Extended Half-Life Monoclonal Antibody Being Developed for the Prevention of Coronavirus Disease (COVID-19)
Not available
S-EPMC8644371 | biostudies-literature
UnknownA phase 2 study of the oral mammalian target of rapamycin inhibitor, everolimus, in patients with recurrent endometrial carcinoma.
Not available
S-EPMC5120730 | biostudies-literature
TranscriptomicsModulation of the immune system during postpartum uterine inflammation [expression]
Post-partum uterine inflammation (endometritis) is associated with lower fertility at both the time of infection and after the inflammation has resolved. It was hypothesized that aberrant DNA methylation may be involved in the sub-fertility associated with post-partum uterine inflammation. The objec...
ORGANISM(S): Bos taurus 
2015-05-07 | E-GEOD-58794 | biostudies-arrayexpress
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