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TranscriptomicsInhibitors that block initiation of wall teichoic acid biosynthesis sensitize methicillin-resistant Staphylococcus aureus to beta-lactams
Methicillin resistance in Staphylococcus aureus depends on the production of mecA, which encodes penicillin-binding protein 2A (PBP2A), an acquired peptidoglycan transpeptidase with reduced susceptibility to beta-lactam antibiotics. Here, we show that preventing the expression of wall teichoic acids...
ORGANISM(S): Staphylococcus aureus 
2010-10-19 | E-GEOD-24439 | biostudies-arrayexpress
TranscriptomicsUnderstanding the Diversity of Maize Cell Wall (affy_cellwall_maize)
affy_cellwall_maize - affy_cellwall_maize - Maize, Zea mays, is one of the most widely grown crops in the world as it provides cereal grain for human purposes and feedstock for cattle. Maize is increasingly used as a biomass fuel, such as ethanol. Studies have shown that maize stem is made up of dif...
ORGANISM(S): Zea mays 
2010-12-07 | E-GEOD-24624 | biostudies-arrayexpress
Transcriptomicsaffy_diversity_maize-Understanding the Diversity of Maize Cell Wall
affy_diversity_maize - affy_diversity_maize - Maize, Zea mays, is one of the most widely grown crops in the world as it provides cereal grain for human purposes and feedstock for cattle. Maize is increasingly used as a biomass fuel, such as ethanol. Studies have shown that maize stem is made up of d...
ORGANISM(S): Zea mays 
2011-07-14 | E-GEOD-22948 | biostudies-arrayexpress
Transcriptomicsaffy_ams_maize-Cell wall maize mutant during arbuscular mycorrhizal symbiosis
affy_ams_maize - aafy_ams_maize - Main objectives of this study: - role of plant cell wall during AM symbiosis - regulation pattern during AM symbiosis - understanding of the original mycorrhizal phenotype of bm4 - search of candidate-genes to study AM symbiosis-After 7 days in phytochambers, plantl...
ORGANISM(S): Zea mays 
2011-05-03 | E-GEOD-22950 | biostudies-arrayexpress
TranscriptomicsHuman bronchial epithelial cells_Passage 3 vs. passage 0
Squamous metaplasia is common in smokers and is associated with airway obstruction in chronic obstructive pulmonary disease (COPD). A major mechanism of airway obstruction in COPD is thickening of the small airway walls. We asked whether squamous metaplasia actively contributes to airway wall thicke...
ORGANISM(S): Homo sapiens 
2007-08-30 | E-GEOD-7557 | biostudies-arrayexpress
MetabolomicsDysregulation of Streptococcus pneumoniae zinc homeostasis breaks ampicillin resistance in a pneumonia infection model

Streptococcus pneumoniae is the primary cause of community-acquired bacterial pneumonia with rates of penicillin and multi-drug resistance exceeding 80% and 40%, respectively. The innate immune response generates a variety of antimicrobial agents to control infection including zinc stres...

2022-02-23 | MTBLS318 | MetaboLights
Transcriptomicsaffy_med_2012_03-Characterization of new phytostimulatrices molecules for the improvement of plants products and crop resistance to diseases
affy_med_2012_03 - affy_med_2012_03 - Aphanomyces euteiches is a major legume parasite related to S. parasitica. Analysis of its cell wall showed the presence of an unsusual high content in GlcNAc, representing 10% of the total carbohydrates. Interestingly, this compound does not form crystalline ch...
ORGANISM(S): Medicago truncatula 
2013-12-01 | E-GEOD-43839 | biostudies-arrayexpress
Transcriptomicsaffy_zeawall_ril2_maize: ZeaWall Project, defavorable parent F271
affy_zeawall_ril2_maize - affy_zeawall_ril2_maize - Four major QTL explaining lignin content and cell wall degradability variation have been identified in the F288 x F271 RIL progeny (Roussel et al., 2002, Maydica 47: 9-20). Gene expression has been considered as a way in identification of candidate...
ORGANISM(S): Zea mays 
2012-08-30 | E-GEOD-27070 | biostudies-arrayexpress
TranscriptomicsReduced atherosclerosis in MyD88 null mice
This series represents a comparison of gene expression in mouse aorta from MyD88-/-, apoE-/- mice versus apoE-/- control mice fed a high fat diet for 8 weeks, causing atherosclerotic lesion development. 5 MyD88-/-, apoE-/- mice were compared to 5 apoE-/- control mice and dye swap replicated for a to...
ORGANISM(S): Mus musculus 
2010-06-09 | E-GEOD-1058 | biostudies-arrayexpress
ProteomicsEpigenetic Control of Drought Acclimation in Sorghum (EPICON): Leaf and Root Proteomics
Two cultivars of Sorghum biocolor were examined from a study performed at the Kearney Research Station in California; 1) a pre-flowering drought tolerant, post-flowering drought susceptible cultivar RTx430 and 2) a pre-flowering drought susceptible, post-flowering drought-tolerant cultivar BTx642. S...
ORGANISM(S): Sorghum Bicolor (ncbitaxon:4558) 
2018-06-21 | MSV000082487 | MassIVE
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