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TranscriptomicsThe Notch driven long non-coding RNA repertoire in T-cell acute lymphoblastic leukemia
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Homo sapiens 
2014-10-27 | E-GEOD-62006 | biostudies-arrayexpress
TranscriptomicsLong noncoding RNA signatures define oncogenic subtypes in T-cell acute lymphoblastic leukemia
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Homo sapiens 
2016-05-17 | E-GEOD-74312 | biostudies-arrayexpress
TranscriptomicsRNA-sequencing of the GSI treatment of the CUTLL1 cell line
Genetic studies in T-cell acute lymphoblastic leukemia have uncovered a remarkable complexity of oncogenic and loss-of-function mutations. Amongst this plethora of genetic changes, NOTCH1 activating mutations stand out as the most frequently occurring genetic defect, identified in more than 50% of T...
ORGANISM(S): Homo sapiens 
2014-10-27 | E-GEOD-61999 | biostudies-arrayexpress
TranscriptomicsDevelopment of gene expression signatures with lncRNAs for GSI treatment of the CUTLL1 cell line.
Genetic studies in T-cell acute lymphoblastic leukemia have uncovered a remarkable complexity of oncogenic and loss-of-function mutations. Amongst this plethora of genetic changes, NOTCH1 activating mutations stand out as the most frequently occurring genetic defect, identified in more than 50% of T...
ORGANISM(S): Homo sapiens 
2014-10-27 | E-GEOD-61869 | biostudies-arrayexpress
TranscriptomicsDevelopment of gene expression signatures with lncRNAs for GSI treatment of T-ALL cell lines
Genetic studies in T-cell acute lymphoblastic leukemia have uncovered a remarkable complexity of oncogenic and loss-of-function mutations. Amongst this plethora of genetic changes, NOTCH1 activating mutations stand out as the most frequently occurring genetic defect, identified in more than 50% of T...
ORGANISM(S): Homo sapiens 
2014-10-27 | E-GEOD-61870 | biostudies-arrayexpress
TranscriptomicsDevelopment of gene expression signatures with lncRNAs for 15 T-ALL patients
Genetic studies in T-cell acute lymphoblastic leukemia have uncovered a remarkable complexity of oncogenic and loss-of-function mutations. Amongst this plethora of genetic changes, NOTCH1 activating mutations stand out as the most frequently occurring genetic defect, identified in more than 50% of T...
ORGANISM(S): Homo sapiens 
2014-10-27 | E-GEOD-61863 | biostudies-arrayexpress
TranscriptomicsDevelopment of gene expression signatures with lncRNAs for 64 T-ALL patient samples
Genetic studies in T-cell acute lymphoblastic leukemia have uncovered a remarkable complexity of oncogenic and loss-of-function mutations. Amongst this plethora of genetic changes, NOTCH1 activating mutations stand out as the most frequently occurring genetic defect, identified in more than 50% of T...
ORGANISM(S): Homo sapiens 
2014-10-27 | E-GEOD-61866 | biostudies-arrayexpress
TranscriptomicsDevelopment of gene expression signatures with lncRNAs for coculture of CD34+ T-cells with an OP9-DLL1 feeder layer
Genetic studies in T-cell acute lymphoblastic leukemia have uncovered a remarkable complexity of oncogenic and loss-of-function mutations. Amongst this plethora of genetic changes, NOTCH1 activating mutations stand out as the most frequently occurring genetic defect, identified in more than 50% of T...
ORGANISM(S): Homo sapiens 
2014-10-27 | E-GEOD-61871 | biostudies-arrayexpress
TranscriptomicsThe role of long noncoding RNAs in T-cell acute lymphoblastic leukemia
T-cell acute lymphoblastic leukemia (T-ALL) is genetically heterogeneous and can be classified into genetic subclasses based on protein coding gene expression profiles. Thus far, long noncoding RNAs (lncRNAs), representing one of the largest fractions of the human transcriptome, remained unexplored ...
ORGANISM(S): Homo sapiens 
2016-05-17 | E-GEOD-74272 | biostudies-arrayexpress
TranscriptomicsRNA-sequencing of CD34+ thymocytes that were cultured on an OP9-GFP or OP9-DLL1 feeder layer.
Genetic studies in T-cell acute lymphoblastic leukemia have uncovered a remarkable complexity of oncogenic and loss-of-function mutations. Amongst this plethora of genetic changes, NOTCH1 activating mutations stand out as the most frequently occurring genetic defect, identified in more than 50% of T...
ORGANISM(S): Homo sapiens 
2014-10-27 | E-GEOD-62000 | biostudies-arrayexpress
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