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ProteomicsDecoding the signalling profile of hematopoietic progenitor kinase 1 (HPK1) in innate immunity: a proteomic approach
The fine-tuned spatiotemporal response of leukocytes to external stimuli is a hallmark of the immune system. Sensing of stimuli occurs through cell surface receptors, which transmit signals into the cell. Signaling via β2 integrins, B cell, and T cell receptors involve similar pathways. However, the...
ORGANISM(S): Homo sapiens (Human) 
2022-02-10 | PXD021136 | Pride
Hematopoietic progenitor kinase 1  interactome  innate immunity  neutrophils 
ProteomicsIdentification of novel Coronin 1A interacting proteins
Severe combined immunodeficiency 8 (IMD8) is caused by mutations in the human Coronin 1A (Coro1A). The clinical presentation of IMD8 patients is characterized by recurrent bacterial infections, suggesting an important role of Coro1A in innate immunity. To analyze the molecular mechanism of Coro1A du...
ORGANISM(S): Homo sapiens (Human) 
2017-06-29 | PXD004635 | Pride
Hl-60 cells Gfp nanotraps Maxquant Coronin 1a Co-immunoprecipitation Lc-ms/ms 
UnknownOrphan GPR84 facilitates uropod de-adhesion at multiple steps during leukocyte extravasation
Not available
S-SCDT-10_1038-S44319-026-00923-0 | biostudies-other
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