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TranscriptomicsLoss of MeCP2 in the rat models regression, impaired sociability and transcriptional deficits of Rett syndrome
The goal of this study was to characterize a novel Mecp2 allele in the laboratory rat, a distinct rodent species from the laboratory mouse with unique features. The allele was created by zinc finger-nuclease (ZFN) targeting (SAGE/Horizon) of the X-linked gene, Methyl-CpG-Binding Protein 2 (Mecp2), r...
ORGANISM(S): Rattus norvegicus 
2016-08-09 | E-GEOD-83323 | biostudies-arrayexpress
TranscriptomicsNLRP7 promotes trophoblast lineage differentiation, YY1 binding and alters CpG methylation
Genome wide DNA methylation profiling of hESC in the untransduced, scrambled control and with knockdown of NLRP7 in undifferentiated and BMP4 differentiated states using the Illumina HumanMethylation 450 BeadChip. Several genomic sites exhibit altered methylation upon knocking down NLRP7. Bisulphite...
ORGANISM(S): Homo sapiens 
2013-11-04 | E-GEOD-45727 | biostudies-arrayexpress
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