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MetabolomicsEffects of Platycodins Folium on Depression in Mice Based on a UPLC-Q/TOF-MS Serum Assay and Hippocampus Metabolomics
Major depressive disorder (MDD), also known as depression, is a state characterized by low mood and aversion to activity. Platycodins Folium (PF) is the dried leaf of Platycodon grandiflorum, with anti-inflammatory and antioxidative activities. Our previous research suggested that PF was rich in fla...
2020-06-03 | MTBLS952 | MetaboLights
TranscriptomicsTranscriptome Sequencing and De Novo Analysis of a Cytoplasmic Male Sterile Line and Its Near-Isogenic Restorer Line in Chili Pepper (Capsicum annuum L.)
Background: The use of cytoplasmic male sterility (CMS) in F1 hybrid seed production of chili pepper is increasingly popular. However, the molecular mechanisms of cytoplasmic male sterility and fertility restoration remain poorly understood due to limited transcriptomic and genomic data. Therefore, ...
ORGANISM(S): Capsicum annuum 
2013-07-03 | E-GEOD-45431 | biostudies-arrayexpress
TranscriptomicsMR-1 nitrate sample to fumarate sample
One of the most striking observations in the S. oneidensis genome regarding nitrate respiration is that napC is missing and nrfBCD is degenerated. To gain insights into candidate genes encoding the protein(s) in place of NapC and NrfBCD function, i.e., delivering electrons to NapA and NrfA, transcri...
ORGANISM(S): Shewanella oneidensis MR-1 
2010-05-19 | E-GEOD-11198 | biostudies-arrayexpress
MetabolomicsUrine metabolomics phenotyping and urinary biomarker exploratory in mild cognitive impairment and Alzheimer's disease.

INTRODUCTION Alzheimer's disease is a prevalent disease with a heavy global burden and is suggested to be a metabolic disease in the brain in recent years. The metabolome is considered to be the most promising phenotype which reflects changes in genetic, transcript, and protein ...

2024-01-11 | MTBLS8662 | MetaboLights
UnknownA successful hybrid deep learning model aiming at promoter identification.
Not available
S-EPMC9158169 | biostudies-literature
ProteomicsSpatial proteomics atlas of Alzheimer's disease
Here, we used laser microdissection combined with high-resolution mass spectrometry technology to construct the brain spatial proteomics map of AD mice and WT mice, aiming to identify the spatial protein distribution characteristics of Alzheimer's disease.
ORGANISM(S): Mus musculus (Mouse) 
2026-06-02 | PXD055958 | Pride
Spatial proteomics Alzheimer's disease Mouse 
TranscriptomicsTranscription profiling of Arabidopsis leaf tissues and protoplasts in response to Plum pox virus infection
Virus infection induces activation and suppression of global gene expression in the host. Profiling gene expression changes in the host may provide insights into the molecular mechanisms that underlie host physiological and phenotypic responses to virus infection. In this study, the Arabidopsis Affy...
ORGANISM(S): Arabidopsis thaliana 
2008-11-07 | E-GEOD-11217 | biostudies-arrayexpress
TranscriptomicsSynergistic Repression of Embryonic Program by SET DOMAIN GROUP 8 and EMBRYONIC FLOWER 2 in Arabidopsis Seedlings
The seed maturation program occurs only during late phase of embryo development and repression of the maturation genes is pivotal for seedling development. However, mechanisms that repress the expression of this program in vegetative tissues are not well understood. A genetic screen was performed fo...
ORGANISM(S): Arabidopsis thaliana 
2011-12-31 | E-GEOD-29771 | biostudies-arrayexpress
UnknownEffects of aerobic exercise and resistance training on obstructive sleep apnea: a systematic review and meta-analysis.
Not available
S-EPMC11530989 | biostudies-literature
ProteomicsProteomic analysis of supernatant from bone marrow mesenchymal stem cells under high glucose condition
We employed a proteomic analysis to identify proteins with altered expression in the extracellular matrix (ECM), aiming to elucidate the underlying mechanism. 
ORGANISM(S): Homo Sapiens 
2023-11-27 | PXD047253 |
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