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ProteomicsImproving sperm cryopreservation with type III antifreeze proteins: effect on proteomic profiles of Cynomolgus macaque sperm
Antifreeze protein III (AFP III) has been used in the cryopreservation of germ cells in several kinds of animals, but it is not yet known what the specific cryoprotective mechanism of AFP III is, except for reducing the formation of ice crystals during cryopreservation. In order to study the cryopro...
ORGANISM(S): Cynomolgus macaque cytomegalovirus strain Mauritius 
2022-02-17 | PXD024836 | Pride
Cynomolgus macaques  sperm  cryopreservation  antifreeze protein iii  proteomic profile 
ProteomicsEasySCP Unveils Extensive Liver Zonation at Single-cell Proteomics Resolution
The widespread adoption of single-cell proteomics (SCP) in biology has been limited by complex workflows and reliance on specialized instrumentation. Here we present EasySCP, a high-throughput and lossless method that integrates FACS-based single-cell sorting, an all-in-one, single-step digestion pr...
ORGANISM(S): Homo Sapiens Mus Musculus 
2025-10-30 | PXD070083 |
ProteomicsSARS-CoV-2 ORF10 impairs cilia by enhancing CUL2ZYG11B activity
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the causal pathogen of the ongoing global pandemic of coronavirus disease 2019 (COVID-19). Loss of smell and taste are new identified symptoms of COVID‐19, and both of these are related to cilia dysfunction. However, the pathological me...
ORGANISM(S): Homo Sapiens 
2022-02-23 | PXD031842 |
TranscriptomicsEpigenome analysis of female identical twins
Genome wide DNA methylation profiling of blood samples from eight female identical twins of Han Chinese for forensic age prediction, age 21 to 32. The Illumina Infinium HumanMethylation450 BeadChip was used to obtain DNA methylation profiles across approximately 485,000 CpGs at a single-nucleotide r...
ORGANISM(S): Homo sapiens 
2015-12-08 | E-GEOD-65638 | biostudies-arrayexpress
ProteomicsA prokaryotic E2 enzyme imitates the ubiquitin pathway to regulate the antiviral cGAS
The cyclic oligonucleotide-based anti-phage signalling system (CBASS) is a typeof innate prokaryotic immune system. Composed of a cyclic GMP-AMP synthase (cGAS) and CBASS-associated proteins, CBASS utilizes cyclic oligonucleotides to activate antiviral immunity. One major class of CBASS contains a h...
ORGANISM(S): Serratia Marcescens Lct-sm213 
2024-02-27 | PXD050178 |
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