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In this study, scapular fat was collected from winter and summer Sunit sheep, and protein sequencing was used to identify key proteins in the process of cold resistance
ORGANISM(S): Ovis Aries 
2024-03-12 | PXD050546 |
Genome-wide maps of cytosine methylation, cytosine hydroxylmethylation and small non coding RNAs in mouse ES cells and upon guided differentiation to mesoendoderm cells. Mouse embryonic stem cells (E14) were guided differentiated into mesoendoderm lineages by activin-A induction. cells in three time...
ORGANISM(S): Mus musculus 
Distinct metabolic programs support the differentiation of CD4+T cells into their separate lineages. In this study, we investigated metabolic mechanisms underlying the differentiation of IL-9 producing-CD4+T cells (TH9) in allergic airway inflammation and cancerous tumors. We found here that SIRT1 n...
ORGANISM(S): Mus musculus 
We generated two types 5-methylcytosine (5-mC) data in E14 mouse embryonic stem cells, using methylated DNA immunoprecipitation followed by sequencing (MeDIP-seq) and DNA digestion by methyl-sensitive restriction enzymes followed by sequencing (MRE-seq). Examination of 2 histone modifications and me...
ORGANISM(S): Mus musculus 
TMT-based proteomic approach was used to compare the liver protein expression profiles of cancer cachexia mice and healthy control mice.
ORGANISM(S): Mus Musculus 
2021-01-11 | PXD023497 |
Mitosis deregulation is a key event during carcinogenesis. Alternative splicing spectrum alteration plays a critical role during mitosis shift. However, the molecules responsible for dysregulated alternative splicing driving carcinogenetic mitosis remain poorly defined. Here, we demonstrate that can...
ORGANISM(S): Homo Sapiens 
Although people of all ages are susceptible to COVID-19, children usually develop less severe disease than adults. Little is known about the pathogenesis of COVID-19 in children. Herein, we conduct the plasma proteomic and metabolomic profiling of a cohort of COVID-19 children patients with mild sym...
ORGANISM(S): Homo Sapiens 
2021-06-28 | PXD026962 |
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