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ProteomicsA comprehensive portrait of tissue-, age- and sex-specific DNA modifications in rodents and humans
DNA damage causes genomic instability underlying many diseases, with traditional analytical approaches providing minimal insight into the spectrum of DNA lesions in vivo. Here we used untargeted chromatography-coupled tandem mass spectrometry-based adductomics (LC-MS/MS) to define the landscape of D...
ORGANISM(S): Homo sapiens (Human) Rattus norvegicus (Rat) 
2023-09-12 | PXD045311 | Pride
Adductomics Strp mrm 
TranscriptomicsThe response and recovery of Arabidopsis thaliana transcriptome to phosphate starvation [At35b_MR]
Background: Over application of phosphate fertilizers in modern agriculture contaminates waterways and disrupts natural ecosystems. Nevertheless, this is a common practice among farmers, especially in developing countries as abundant fertilizers are believed to boost crop yields. The study of plant ...
ORGANISM(S): Arabidopsis thaliana 
2012-06-17 | E-GEOD-33996 | biostudies-arrayexpress
TranscriptomicsThe response and recovery of Arabidopsis thaliana transcriptome to phosphate starvation [ATH1-121501]
Background: Over application of phosphate fertilizers in modern agriculture contaminates waterways and disrupts natural ecosystems. Nevertheless, this is a common practice among farmers, especially in developing countries as abundant fertilizers are believed to boost crop yields. The study of plant ...
ORGANISM(S): Arabidopsis thaliana 
2012-06-17 | E-GEOD-33790 | biostudies-arrayexpress
TranscriptomicssmRNA under high osmotic stress
To identifiy osmotic stress responsive smRNAs, we used a deep-sequencing technique to profile small RNA populations in leaf and root tissues of plants under high osmotic stress and control conditions. We treated 30day-old plants with high osmotic stress and sampled leaves and roots from the same pla...
ORGANISM(S): Arabidopsis thaliana 
2012-09-19 | E-GEOD-36560 | biostudies-arrayexpress
GenomicsThree distinct patterns of histone H3Y41 phosphorylation mark active genes
The aim of the project was to identify the global distribution of H3Y41ph and correlate its presence with the transcription factor STAT5 and the active histone modification H3K4me3. This was done in human erythroid leukaemia cells (HEL). HEL cells were treated with DMSO or a JAK2 inhibitor (TG101209...
ORGANISM(S): Homo sapiens 
2013-04-15 | E-MTAB-1096 | biostudies-arrayexpress
GenomicsGenome-wide analysis of GATA1, GATA2, RUNX1, FLI1 and SCL binding in primary human megakaryocytes
We have mapped the binding sites for the five key regulators GATA1, GATA2, RUNX1, FLI1 and TAL1/SCL in primary human megakaryocytes. Statistical analysis identified subsets of enriched as well as depleted combinatorial binding patterns. In particular simultaneous binding by all 5 factors was highly ...
ORGANISM(S): Homo sapiens 
2011-06-01 | E-GEOD-24674 | biostudies-arrayexpress
UnknownFatty acid profiles of great tit (Parus major) eggs differ between urban and rural habitats, but not between coniferous and deciduous forests.
Not available
S-EPMC4908168 | biostudies-literature
TranscriptomicsSingle-cell RNA sequencing data of zebrafish lymphatic and venous endothelial cells at different developmental stages (36 hpf, 48 hpf, 120 hpf (5 dpf) and 168 hpf (7 dpf))
This dataset contains single-cell RNA sequencing (scRNA-seq) profiles of zebrafish venous and lymphatic endothelial cells across development. Endothelial cells were isolated by FACS from transgenic zebrafish embryos and larvae at 36 hpf, 48 hpf, 5 dpf (120 hpf), and 7 dpf (168 hpf) using endothelial...
ORGANISM(S): Danio rerio 
2026-09-28 | E-MTAB-16797 | biostudies-arrayexpress
TranscriptomicsTranscriptome Profiling of Roots and leaves Under High Osmotic Stress in Arabidopsis
The functions of miRNAs and their target mRNAs in Arabidopsis development have been widely documented, however, roles of stress responsive miRNAs and their targets are not as well understood. Using small RNA deep sequencing and ATH1 microarrays to profile mRNAs, we identified IAR3 (IAA-Ala Resistant...
ORGANISM(S): Arabidopsis thaliana 
2012-09-19 | E-GEOD-36789 | biostudies-arrayexpress
UnknownThe response and recovery of the Arabidopsis thaliana transcriptome to phosphate starvation.
Not available
S-EPMC3520718 | biostudies-literature
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