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UnknownA tombus-like virus in patients with lower respiratory tract infection: an observational study based on meta-transcriptomic sequencing.
The identification of a novel virus related to the family Tombusviridae, provisionally named human tombus-like virus (hTLV), is significant in the context of ongoing surveillance for respiratory pathogens. Meta-transcriptomic sequencing was utilized to detect respiratory pathogens in patients...
S-EPMC12024507 | biostudies-literature
UnknownSKP2 Activation by Thyroid Hormone Receptor β2 Bypasses Rb-Dependent Proliferation in Rb-Deficient Cells.
Germline RB1 mutations strongly predispose humans to cone precursor-derived retinoblastomas and strongly predispose mice to pituitary tumors, yet shared cell type-specific circuitry that sensitizes these different cell types to the loss of RB1 has not been defined. Here we show that th...
S-EPMC5732859 | biostudies-literature
ProteomicsMeasurement of site-specific H2O2-sensitivity and identification of sulfenic acid modification of CLOCK cysteines
In vitro H2O2-sensitivity of CLOCK cysteines was measured with a quantitative chemoproteomic approach termed as QTRP (Quantitative Thiol Reactivity Profiling) as previously reported. In brief, 5 μg of recombinant CLOCK proteins were reduced with 1 mM DTT for 30 min at room temperature. After reactio...
ORGANISM(S): Homo Sapiens Mus Musculus 
PXD015266 |
Proteomicsmouse liver concatenated tandem array of consensus TF response elements (catTFRE) with H2O2
a pull-down assay using a concatenated tandem array of consensus TF response elements (catTFRE) to trap the TFs expressed in mouse livers following treatment with or without H2O2
ORGANISM(S): Mus Musculus 
PXD015265 |
ProteomicsProteomic analysis hippocampus in TLE rats
iTRAQ coupled with LC-MS/MS was applied for proteomic analysis of hippocampus.
ORGANISM(S): Rattus Norvegicus 
2022-04-27 | PXD033481 |
UnknownEmerging tobacco-related cancer risks in China: A nationwide, prospective study of 0.5 million adults.

Background

In China, cigarette consumption has increased substantially since the 1980s, almost exclusively in men. This study was aimed at assessing the emerging cancer risks.

Methods

A nationwide, prospective study recruited 210,259 men and 302,632 women aged 30 to 79 years from 10 a...
S-EPMC4584499 | biostudies-literature
UnknownExtracting the femtometer structure of strange baryons using the vacuum polarization effect.
One of the fundamental goals of particle physics is to gain a microscopic understanding of the strong interaction. Electromagnetic form factors quantify the structure of hadrons in terms of charge and magnetization distributions. While the nucleon structure has been investigated extensively, data on...
S-EPMC11470094 | biostudies-literature
UnknownGuidelines for the use and interpretation of assays for monitoring autophagy (3rd edition).
Not available
S-EPMC4835977 | biostudies-literature
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