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ProteomicsMetabolic characterization of hepatic disease patients with hepatitis B virus DNA replication by untargeted metabolomics
Purpose: Worldwide, over 350 million people are chronically infected with the hepatitis B virus (HBV) and are at increased risk of developing progressive hepatic diseases (hepatitis, cirrhosis or liver cancer). Still, the metabolic processes operational during the distinct clinical phases of a chro...
ORGANISM(S): Homo Sapiens 
2021-05-13 | PXD025989 |
ProteomicsProteomic analysis of liver cancer under drug treatment
we employed a tandem mass spectrometry-based quantitative proteomics strategy to perform a comprehensive analysis of protein expression profiles in the HepG2 following treatment with three clinically relevant liver cancer drugs, identifying a total of 8,036 proteins.
ORGANISM(S): Homo Sapiens 
2024-10-23 | PXD057086 |
ProteomicsThe influence of different Matrigel dissolving methods on proteome research of human derived organoids
Here we investigated the influence of different Matrigel dissolving methods on organoid proteomics.
ORGANISM(S): Homo Sapiens Mus Musculus 
2021-10-12 | PXD029173 |
ProteomicsPhospho-proteomics enables classification of cancer subtypes and nomination of druggable kinases for individual patients of diffuse-type gastric cancer
The diffuse-type gastric cancer (DGC) constitutes a subgroup of gastric cancer with poor prognosis and no effective molecular therapies. Here, we report a phosphoproteomic landscape of DGC derived from 83 tumors together with their nearby tissues. Based on phosphorylation, DGC could be classified in...
ORGANISM(S): Homo Sapiens 
2020-03-31 | PXD018293 |
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